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Associate Scientist II
675 West Kendall Street Cambridge, MA 02142 US
Job Description
Overview:
The successful candidate will be a part of the Process Chemistry group, responsible for the process development and in-house non-GMP manufacture of modified oligonucleotides and siRNAs.
Summary of Key Responsibilities:
- Support non-GMP oligonucleotide production on a tight timeline
- Support purification method development, optimization, and scale-up
- Execute non-GMP oligonucleotide purifications
- Execute downstream processing of purified material
- Execute in-process analytical tests
- Participate in creating and reviewing SOPs and batch records
- Support campaign activities across other unit operations as-needed
Qualifications:
- BS in Chemistry with 1-3 years lab experience, preferably in an industrial setting.
- Basic understanding of analytical techniques (pH, osmolality, conductivity measurement, HPLC, LC-MS etc.). Related hands-on experience is preferred. Knowledge of oligonucleotide manufacture process including phosphoramidite chemistry, chromatography, ultrafiltration etc. is a plus.
- Experience in record-keeping and excellent laboratory documentation practice, are required. Strong commitment to high laboratory and scientific standard; ability to maintain a safe, clean, and orderly laboratory work environment; assist in routine lab and equipment maintenance.
- Good communication skill is a must for this position. The successful candidate must be a responsible and proactive individual who is able to work as a team player in a highly dynamic environment with aggressive timelines.
Equal Opportunity Employer: We are proud to be an equal opportunity employer. We welcome and encourage applications from all qualified candidates regardless of race, sex, gender identity or expression, disability, age, religion or belief, sexual orientation, or any other characteristic protected by applicable laws and regulations. It is our policy not to discriminate against any applicant or employee, and we are committed to fostering a diverse, inclusive, and respectful work environment across all locations in which we operate. We believe that diversity, equity, and inclusion are fundamental to our mission and enhance our ability to serve clients globally. If you have a disability or require any reasonable accommodations during the application or interview process, please inform your recruiter or contact us directly so that we can explore the appropriate arrangements.
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