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Scientist III
1000 Gateway Blvd. South San Francisco, CA 94080 US
Job Description
Target PR Range: 63-73/hr
*Depending on experience
Precision Medicine Pathology
The Precision Medicine Pathology team drives the scientific strategy for translational tissue-based biomarker development & discovery target validation/MOA projects, leads pathology collaborative programs, conducts histopathological evaluation & analysis of IHC & other tissue-based studies, and provides technical/scientific leadership to histotechnicians & pathology scientists.
In this role, you will be supporting a variety of studies using multiplex immunofluorescence assays. You must be able to conceive and implement multiplex IF assays to answer scientific questions.
Responsibilities:
· Designing, developing and validating multiplex immunofluorescence panels using OPAL or similar technologies.
o Designing an mIF panel with consideration of biologic & technical factors
o Developing & optimizing the mIF panel
o Scanning mIF slides using PhenoImager HT
o Spectral unmixing using inForm
· Digital pathology analysis using Halo or VisioPharm
· Expected to make significant contributions to project team through lab-based activities
· Highly autonomous and productive in performing laboratory research or method development
· Formulate conclusions and design follow-on experiments based on multidisciplinary data
Qualifications:
· Bachelor’s Degree in Science related field with 5+ years of related work; Master’s Degree Science with 10+ years of related work.
· Close familiarity with the principles of tissue microscopic anatomy/histology including knowledge of pathological alterations in disease and experience working in collaboration with trained pathologists is preferred.
· Extended experience in designing, developing & validating multiplex mIF assays using OPAL or similar technologies, as well as scanning the mIGF stained slides & spectral unmixing using inForm.
· Experience in digital image analysis using Halo or VisioPharm.
· Excellent verbal communication skills are required including the demonstrated ability to effectively and clearly summarize results for presentation and report generation
· Strong motivation, attention to detail, ability to think independently and fully integrate into a high achieving team environment
· Ability to multi-task and manage multiple projects
Equal Opportunity Employer: We are proud to be an equal opportunity employer. We welcome and encourage applications from all qualified candidates regardless of race, sex, gender identity or expression, disability, age, religion or belief, sexual orientation, or any other characteristic protected by applicable laws and regulations. It is our policy not to discriminate against any applicant or employee, and we are committed to fostering a diverse, inclusive, and respectful work environment across all locations in which we operate. We believe that diversity, equity, and inclusion are fundamental to our mission and enhance our ability to serve clients globally. If you have a disability or require any reasonable accommodations during the application or interview process, please inform your recruiter or contact us directly so that we can explore the appropriate arrangements.
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