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Associate Scientist - Research Scientist, Neuroscience

New Haven, CT 06511

Posted: 07/01/2024 Employment Type: Contract Job Category: Scientific Job Number: 607582 Is job remote?: No Country: United States

Job Description

Position Summary:
This is an exciting opportunity to join our growing Neuroscience team. As client's portfolio of preclinical and clinical programs continues to expand, the candidate for this postion will have a tremendous opportunity to help us drive our translational strategy for current and upcoming clinical stage neuroscience PROTAC drug candidates. We are seeking a highly motivated and collaborative candidate who is passionate about advancing novel  neurodegeneration therapies for a laboratory-based position.  This individual will have strong experimental skills and will utilize a variety of techniques to profile pharmacokinetic-phamacodynamic properties and downstream functional mechanisms of PROTAC drug candidates.
This position reports to a Senior Director, Neuroscience and will be located at our headquarters in New Haven, CT.

Principal Responsibilities:
As part of the Neuroscience team, the candidate will assist in the assessment of target engagement, pathway engagement and evaluation of pharmacokinetic and pharmacodynamic (PK/PD) relationships as part of ongoing preclinical research studies across multiple programs. Key responsibilities of this role include, but are not limited to:
  • Independently design and execute experiments, and perform data analysis
  • Leverage multiple assay platforms to assess mechanisms/pathways associated with PROTAC degrader molecules
  • Interact and collaborate with neuroscience, chemistry, translational and clinical team members to contribute to drug discovery and development program progression
  • Document, compile and interpret experimental data; manage electronic laboratory notebook, databases, and/ or spreadsheets to present data in a meaningful manner
  • Keep up-to-date on relevant scientific literature
Qualifications:
  • Cell culture (cell lines, iPSC-derived neurons, primary neurons); including cell line maintenance, transfection, and compound treatment
  • Ex vivo and/or clinical sample handling and processing for protein extraction and detection
  • Proficient in molecular and cellular biology techniques and biochemical assays, including but not limited to immunoblotting, ELISA, and MSD
  • Biomarker expierence is a plus
  • Plate-based assay development and validation experience is desirable
  • Innovative and creative individual with the ability to work independently and in a team environment, prioritize experimental design and data analysis, and take ownership of multiple projects
  • Well organized and demonstrated ability to prepare technical reports, summaries, protocols,etc.
  • Highly motivated with strong interpersonal and communication skills
Education:
  • MS in biological sciences with a minimum of 5 years of related experience; previous industry experience is a plus.
  • Neuroscience background or understanding is preferred but not required

The staffing industry has seen an increase in people falsely representing themselves as recruiters to gather personal information from job seekers. For your safety, do not provide sensitive data to anyone you have not spoken with thoroughly and never provide banking information during the application process. Candidate safety is a top priority at Planet Pharma.

Planet Pharma and The Planet Group of Companies are equal opportunity employers. It is our practice not to discriminate against any employee or applicant based on any criteria, condition or basis protected by laws or regulations in the locations where we do business. All qualified applicants are encouraged to apply. We celebrate diversity and are committed to providing an environment of mutual respect. We believe that diversity, equity and inclusion enable us to better meet our mission and values while serving our clients across the globe. If you have a disability or handicap and would like us to accommodate you in any reasonable way, please inform your recruiter, or contact us, so that we can discuss the appropriate alternatives available.

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About New Haven, CT

Ready to launch your career in the vibrant area around New Haven, Connecticut? Explore a plethora of exciting job opportunities in this bustling hub of innovation and culture. Boasting renowned landmarks like Yale University, the historic Shubert Theatre, and the stunning New Haven Green, this region offers a perfect blend of urban charm and natural beauty. With a thriving arts scene, delectable cuisines like the classic New Haven-style pizza, and an array of outdoor recreation options at East Rock Park and Long Wharf, this area is a haven for career growth and work-life balance. Join us in discovering the endless possibilities that await your professional journey in this enchanting corner of the Constitution State.

Although this hasn't been an issue at Planet Pharma, the staffing industry has seen an increase in people falsely representing themselves as recruiters to gather personal information from job seekers. For your safety, do not provide sensitive data to anyone you have not spoken with thoroughly and never provide banking information during the application process. Candidate safety is a top priority at Planet Pharma.