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Bio-Conjugation Scientist

S San Francisco, CA 94080

Posted: 08/13/2024 Employment Type: Contract Job Category: Scientific Job Number: 613793 Is job remote?: No Country: United States

Job Description


Please focus on:
  • This is a Bio-conjugation Scientist role, so please advertise it as per this title to get the relevant resumes and candidates’ applications.
  • Hands on experience with conjugation, purification and characterization of antibody drug conjugates.
  • Experience using analytical techniques/instrumentation, including chromatographic techniques such as HIC (Hydrophobic Interaction Chromatography) and RP (Reverse Phase) and SEC(Size Exclusion Chromatography).

Comments/Special Instructions
This is a Bio-conjugation Scientist role. Please submit your best 2 qualified candidates. Minimum 8 years of relevant industry experience is needed with BS/MS and 5 years with PHD.

Required: Hands on experience with conjugation, purification and characterization of antibody drug conjugates, and experience using analytical techniques/instrumentation, including chromatographic techniques such as HIC (Hydrophobic Interaction Chromatography) and RP (Reverse Phase), SEC, SDS-PAGE, UV?Vis.
Responsibilities:
This is a Bio-conjugation Scientist role with MRL SSF Discovery Chemistry group.

This company is currently seeking highly motivated and exceptional a Bio-conjugation Scientist for positions within the Discovery Chemistry Department located at our South San Francisco, CA site.

• The successful candidate will join multidisciplinary, highly collaborative discovery teams to invent novel medicines by applying optimized conjugation protocols, analytical techniques, and data analysis to synthesize drug candidates and intermediates.
• Successful candidates must have excellent interpersonal, collaboration, and communication skills in a team environment.
• Additionally, it is expected that the successful candidate will learn quickly through on-the-job training to become increasingly skilled and independent in reaction setup, route design and optimization. Specific responsibilities will include:
• Perform bioconjugations of linker-payload combinations to antibodies with emphasis on in-house established methods
• Selection and application of appropriate purification techniques for biologics (i.e., SEC, hydrophobic interaction chromatography, ion exchange chromatography)
• Acquisition and interpretation of analytical data such as LC/MS.

Qualifications: This is a Bio-conjugation Scientist role, so please advertise it as per this title to get the relevant resumes and candidates’ applications.
Education Requirement:
• Minimum qualifications include a B.S./M.S/ PHD in chemistry, biochemistry, or related field, with industrial or academic experience. Experience and Skills Required:
• Hands on experience with conjugation, purification and characterization of antibody drug conjugates, and experience using analytical techniques/instrumentation, including chromatographic techniques such as HIC (Hydrophobic Interaction Chromatography) and RP (Reverse Phase), SEC, SDS-PAGE, UV?Vis. • Nice to have skills: Biologics analytic experience, purification techniques.
• Must have: Bio-conjugation experience, protein biochemistry and Chemistry background.
• Personality: Team player, Adheres to timeline, Communicative and collaborative.
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