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Biologist II

Worcester, MA 01605

Posted: 08/24/2023 Employment Type: Contract Job Category: Scientific Job Number: 582515 Is job remote?: No Country: United States

Job Description

Target PR Range: 30-38/hr
*Depending on experience
Description Details

Contract position Biologist II- ADC Platform

 

The ADC (Antibody Drug Conjugates) platform group within SMTPT (Small Molecule Therapeutics & Platform Technologies. ADC Platform group collaborates with drug discovery project teams across all Company therapeutic areas including Oncology and Immunology. The ideal candidate will effectively work to collaborate with chemists, biologists and pharmacologists to characterize large and small molecules for ADC development.

 

Key Responsibilities:

· Design and execute in vitro assays for screening of biologics, small molecules and antibody drug conjugates

o Reporter, cytokine release, cell killing and antibody internalization assays

· Generate and characterize transient and stable cell lines to support antibody drug conjugate programs.

o Lipid transfection and lenti viral infections

· Characterize lead molecules and confirm mechanism of action

· Work collaboratively with project teams to deliver targets across portfolio

· Demonstrate scientific excellence, work ethic, and dedication to team and project goals

· Work collaboratively in a matrix with project teams and members of the Biologics Group to drive innovation and deliver novel therapies to patients

· Develop productive collaborations and communication with other groups across therapeutic areas

Basic Qualifications:

· Bachelor’s degree in related discipline with 3 or more years of experience and a BS in Biology or Biochemistry

· Experienced screening antibodies, small molecules and siRNAs (reporter assays, proliferation and cytokine release)

· Experience executing antibody internalization and siRNA loss of function studies is a plus

· Experience with transfections and generating transient and stable cell lines

· Experience culturing adherent, suspension and primary cells

· Proficiency in performing flow cytometry and western blot experiments

· Experience with performing qPCR and automated western blot analysis

· Experience working with high throughput laboratory workflows and instruments such MACsQuant, FACS Canto, Microbeta, Wes, Amnis Imagestream, Via7 (taqman) and Spectramax plate readers.

· Experience documenting experimental methods and results into BIOELN

· Ability to summarize and present results to project teams

The staffing industry has seen an increase in people falsely representing themselves as recruiters to gather personal information from job seekers. For your safety, do not provide sensitive data to anyone you have not spoken with thoroughly and never provide banking information during the application process. Candidate safety is a top priority at Planet Pharma.

Planet Pharma and The Planet Group of Companies are equal opportunity employers. It is our practice not to discriminate against any employee or applicant based on any criteria, condition or basis protected by laws or regulations in the locations where we do business. All qualified applicants are encouraged to apply. We celebrate diversity and are committed to providing an environment of mutual respect. We believe that diversity, equity and inclusion enable us to better meet our mission and values while serving our clients across the globe. If you have a disability or handicap and would like us to accommodate you in any reasonable way, please inform your recruiter, or contact us, so that we can discuss the appropriate alternatives available.

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About Worcester, MA

Ready to discover exciting job opportunities in the vibrant city of Worcester, Massachusetts? Join us in exploring a region brimming with growth potential and unique charm. From the majestic Worcester Art Museum to the exhilarating performances at the Hanover Theatre, this culturally rich area offers a blend of history and modernity like no other. Indulge in the local delicacies like the famous Worcester-style pizza, while catching a game of the Worcester Red Sox at Polar Park. Surrounded by lush parks and recreational areas like Elm Park and Green Hill Park, Worcester provides the perfect backdrop for a fulfilling career. Dive into our job listings and unlock a world of possibilities in this captivating city!

Although this hasn't been an issue at Planet Pharma, the staffing industry has seen an increase in people falsely representing themselves as recruiters to gather personal information from job seekers. For your safety, do not provide sensitive data to anyone you have not spoken with thoroughly and never provide banking information during the application process. Candidate safety is a top priority at Planet Pharma.