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Cell Engineering Scientist

SOUTH SAN FRANCISCO, CA 94080

Posted: 11/21/2023 Employment Type: Direct Hire/Perm Job Category: Engineering Job Number: 590452 Is job remote?: No Country: United States

Job Description

As a Cell Engineering Scientist, you will advance our genetic medicine technologies, enabling the discovery and development of new therapeutics. Working with a diverse team of cell biologists, protein and RNA engineers, computational scientists, molecular biologists, and translational biologists, you will:
  • Build improved CRISPR-Cas-related and novel systems that enable therapeutic genome and transcriptome engineering
  • Identify specific genomic targets and develop candidate strategies for therapeutic intervention using our technology portfolio       
  • Comprehensively characterize the genotypic changes induced by candidate therapies, including efficacy, specificity, oncogenic potential, etc.
  • Assess the functional impact of therapeutic candidates using appropriate in vitro and in vivo model systems
  • Develop in vivo delivery approaches for candidate therapies using AAV, LNP, or other platforms
  • Support IND-enabling studies including toxicology, CMC, immunology, and related
  • Maintain comprehensive, accurate records to support scientific best practices, diligence, IND submissions, etc.  
  • Mentor and manage junior scientists/associates by leading discussions of new ideas and/or approaches, challenging ideas and interpretations, and cultivating teams to help solve challenging experimental questions

Requirements:
  • A PhD in a biological discipline, or a masters with a minimum of four years of experience in independent experimental design, focused on bioengineering to change the behavior of cells through control of the genome or transcriptome
  • A creative thinker with a track record of high-quality data generation
  • An experimentalist ready and able to drive to the full cycle of design/build/test/analyze
  • Strong understanding of cell engineering and tissue culture best practices


Preferred Qualifications:
  • Demonstrated track record of characterizing, developing, and optimizing genome or transcriptome modification systems
  • Experience using CRISPR-Cas or similar gene editing tools for therapeutic applications
  • Experience with therapeutic target selection and optimization 
  • Experience engineering protein-DNA and/or protein-RNA interactions
  • Experience establishing pooled or other high throughput screens
  • Demonstrated ability to work in multi-disciplinary teams to achieve experimental objectives

The staffing industry has seen an increase in people falsely representing themselves as recruiters to gather personal information from job seekers. For your safety, do not provide sensitive data to anyone you have not spoken with thoroughly and never provide banking information during the application process. Candidate safety is a top priority at Planet Pharma.

Planet Pharma and The Planet Group of Companies are equal opportunity employers. It is our practice not to discriminate against any employee or applicant based on any criteria, condition or basis protected by laws or regulations in the locations where we do business. All qualified applicants are encouraged to apply. We celebrate diversity and are committed to providing an environment of mutual respect. We believe that diversity, equity and inclusion enable us to better meet our mission and values while serving our clients across the globe. If you have a disability or handicap and would like us to accommodate you in any reasonable way, please inform your recruiter, or contact us, so that we can discuss the appropriate alternatives available.

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Although this hasn't been an issue at The Planet Group, the staffing industry has seen an increase in people falsely representing themselves as recruiters to gather personal information from job seekers. For your safety, do not provide sensitive data to anyone you have not spoken with thoroughly and never provide banking information during the application process. Candidate safety is a top priority at The Planet Group.

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