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Computational Scientist: Human Genetics,
1 DNA Way S San Francisco, CA 94080 US
Job Description
The Human Genetics department at the client site is seeking a highly independent computational scientist with a strong hands-on analytical background in genetic epidemiology, statistical genetics, or computational biology, to develop and apply analytical approaches to integrate and interpret genetic, genomic, and clinical data. We are particularly interested in candidates with skill sets that position them to tackle the integration of multiple sources of human biological data, such as whole genome sequencing and single cell RNA-Seq/ATAC-Seq data, including knowledge of emerging multimodal data integration methods.
This will be a full time contract position until the end of 2025, with the possibility of extension. This is available either as a hybrid or remote position and would ideally be based in a US-friendly time zone.
Responsibilities:
- Collaborate with scientists in Human Genetics department to analyze large datasets of genetic, genomic, and clinical data from internal studies (including our clinical trials and high throughput screens), collaborations with academic and industry partners, and public external data sets
- Develop analytical approaches to integrate and interpret these data, delivering insights into disease biology to propel our translational goals
- Coordinate the intake and preparation of new datasets as they become available for analysis
- Document process, findings, and code
- Present findings to the department and cross-functional collaborators and contribute to publications
Requirements:
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Extensive experience in large-scale genetic/genomic data analysis including one or more of the following areas of expertise:
Understanding of principles of genetic epidemiology Association analysis with array- and sequence-based genetic data Analysis of sequence-based molecular assay data (eg RNA-Seq) including differential expression methods, single-cell sequencing data (eg scRNA-Seq, scATAC-Seq) and/or proteomic data Integration of genetic and molecular data for multimodal analyses
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PhD (or Masters with significant experience) in Statistical Genetics, Computational Biology, Bioinformatics, Genetic Epidemiology, or a related field
- Fluent in R, python, and shell scripting. Some familiarity with C++ will be a plus
- Experience working with git and high performance computing (e.g. the slurm scheduling manager)
- Curiosity and desire to learn more about human genetics, bioinformatics, and biology
- Ability to produce high-quality analysis results with minimal supervision. This includes meeting key deadlines and making sensible independent decisions
- Good communication skills and experience working as part of a team
Pay Rate Range: $50-63/hr depending on experience
Equal Opportunity Employer: We are proud to be an equal opportunity employer. We welcome and encourage applications from all qualified candidates regardless of race, sex, gender identity or expression, disability, age, religion or belief, sexual orientation, or any other characteristic protected by applicable laws and regulations. It is our policy not to discriminate against any applicant or employee, and we are committed to fostering a diverse, inclusive, and respectful work environment across all locations in which we operate. We believe that diversity, equity, and inclusion are fundamental to our mission and enhance our ability to serve clients globally. If you have a disability or require any reasonable accommodations during the application or interview process, please inform your recruiter or contact us directly so that we can explore the appropriate arrangements.
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