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Director of Biology - Immunology

Newark, CA 94560

Posted: 09/15/2023 Employment Type: Direct Hire/Perm Job Category: Scientific Job Number: 572737 Is job remote?: No Country: United States

Job Description

Director,  Biology ( immunology/Inflammation )

Job description

The drug discovery and development team is seeking a highly motivated Project Leader for a full-time research position.  The individual is expected to direct project-based research involving in vitro and in vivo experimentation, work collaboratively and independently in support of multiple Immunology/Inflammation research programs.
Key responsibilities:
  • Leads the biology portions of our Immunology and Inflammation-based projects towards clinical candidate selection.  This includes the development and support of cell-based discovery screening, plate-based reporter, and ELISA assays, as well as flow cytometry
  • Project leadership. Collaborate closely with chemistry, biology, and DMPK, pharmacology groups to drive discovery and lead optimization and pre-clinical characterization of multiple candidates across a different immunology discovery program for clinical candidate selection
  • Responsible for discovery through candidate selection and support of resulting clinical filings ensuring a smooth transition from research to development
  • Analyze, interpret, summarize, and communicate scientific data from the different biology workstreams to the project team
  • Lead and/or assist in writing and revising technical documents including testing protocols and data reports
  • Support data analysis and reporting per needs of the project(s) and maintain contemporaneous database updates
  • Ensure practices and processes of research efforts are up-to-date and meet industry standards
  • Also responsible to keep abreast of competitive landscape based upon project target and indication(s) in development

Requirements
  • Ph.D. in Immunology, Biology, Cell Biology, Molecular Biology, or related fields, and 10+ years of therapeutic industrial research experience
  • Experience with project leadership and leading drug discovery programs
  • Experience with early-phase drug discovery and development with a solid understanding of the immune/inflammation area covering both in vitro and in vivo approaches
  • Demonstrated expertise and a track record of success in advancing discovery programs from target validation through lead optimization and clinical candidate selection
  • Proficiency in the following techniques: screening assays, maintaining cells lines, cell-based assays, flow cytometry, and ELISA
  • Experience with handling of tissue samples from pre-clinical models, blood-based and primary cell-based experiments, and experience in molecular biology techniques is helpful
  • Experience managing work of direct reports, external CROs, KOLs, research advisors, and collaborator activities
  • The ability to simultaneously manage and progress multiple tasks is requisite
  • Proficiency with software such as GraphPad Prism, flow cytometry software and Microsoft Office, for data analysis, figure generation, data management and uploading
  • Attention to detail with excellent organizational, experimental data recording and time management skills
  • A track record of effectively communicating scientific concepts and strategies, including a publication record in top-tier, peer-reviewed journals
  • The ability to develop new skillsets and knowledge will be necessary to successfully support assigned projects
  • Ability to interact effectively with team members and function collaboratively in a highly productive, dynamic, and fast-paced environment
  • Strong verbal and written communication skills
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About Newark, CA

Explore exciting job opportunities in and around Newark, California! Situated in the heart of the San Francisco Bay Area, Newark offers an unbeatable blend of career advancement and quality of life. With easy access to Silicon Valley and major tech companies, as well as the cultural delights of nearby Berkeley and Oakland, this area is a magnet for innovative professionals. Enjoy the stunning views from Mission Peak Regional Preserve, indulge in diverse cuisines along the Niles Canyon Railway, catch a show at the Fremont Center for the Arts, or cheer on the San Jose Earthquakes soccer team at Avaya Stadium. Discover why Newark, CA is the perfect place to grow your career and explore new horizons!

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