Research Associate - Protein Science
5703 Hollis Street Emeryville, CA 94608 US
Job Description
Position Summary:
We are seeking a Research Associate who will be responsible for the production and purification of antibodies and related therapeutic proteins. This position is based in Emeryville, CA, easily accessible by BART / EmeryGoRound, AMTRAK, or car (with private, secured, on-site parking provided.)
We have developed a proprietary approach for site-specific bioconjugation to produce next-generation ADCs. This technology, termed SMARTag, is based on use of the aldehyde-tag site-specific protein modification technology and our novel conjugation chemistry and proprietary, stable linkers. SMARTag is a clinical-stage technology, with its first ADC-TRPH-222-in Phase 1 clinical trials.
The site comprises a close-knit team of scientists working cross-functionally with each other to nimbly achieve our goals and milestones. We are a research site, working to develop therapeutic ADC drug candidates for clinical testing. We also continuously strive to improve and expand our technology platform. The team has a focus on publishing results and contributing to the exciting and dynamic field of bioconjugation and drug conjugates.
Key Competencies
- Hands-on experience with cloning, mammalian cell cultures and aseptic techniques are required.
- Cloning (Gibson assembly), Mini, Maxi, Giga preps, DNA sequence confirmation
- Support the protein production by small- and large-scale transient transfection.
- Experience with Vi-CELL, Octet and HPLC is required.
- Experience in protein characterization assays such as concentration, endotoxin measurement, SDS-PAGE and SEC-HPLC is required.
- Experience in antibodies and other protein purification techniques is preferred.
- Experience using AKTA instruments is preferred.
Requirements
- BS in biology, biochemistry, or a related discipline. BS with 0+ years of relevant experience.
- >1 year of experience in a research lab environment, preferably including work under sterile conditions
Personal Characteristics
The successful candidate must possess the following characteristics:
- A high degree of personal and professional integrity
- Strong interpersonal and communication skills
- Ability to deliver high quality results
- Thrives in a fast-paced environment
- Can adjust to changing situations, providing ideas and solutions
Pay Rate Range: $35-45/hr. Salary will be commensurate with experience
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