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Research Associate II
1 DNA Way S San Francisco, CA 94080 US
Job Description
The Advanced Cell Engineering (ACE) Hub in the Molecular Biology department is seeking a talented and enthusiastic candidate for a full-time lab-based contractor position. The Molecular Biology Department at Genentech focuses on technology innovation to lay groundwork for therapeutic programs centered around cells, genes, and nucleic acids. The ACE Hub in the Molecular Biology Department is an interdisciplinary team with a mission to accelerate drug discovery in early R&D through the development, application, and enablement of genome engineering and synthetic biology technologies.
The successful candidate will support the needs of the ACE Hub, particularly in the engineering and profiling of cell lines for disease modeling used across the organization. They will be expected to work independently and make technical contributions within a dynamic, fast-paced and highly collaborative research environment. This is a one-year position with the possibility of extension.
Responsibilities:
- Generate engineered cell lines using methods including stable integration (both lentivirus and piggybac) and CRISPR gene editing
- Transfection/ gene editing optimization in cell lines
- Troubleshoot protocols Instrument maintenance
- Maintain and quality check cell lines in culture
- Maintain lab safety compliance
Who You Are (Requirements):
- A self-motivated candidate with a (BS/ MS) + 3 years industry experience, or PhD in Molecular Biology, Cell Biology, Genetics, or a related discipline.
- Qualified candidates must have demonstrable strong mammalian cell culture techniques and ability to generate high-quality data.
- Candidates should have excellent written and verbal communication skills, and will be required to analyze and present data at team meetings.
- The candidate should be team-oriented, highly organized both operationally and in silico, with the ability to multi-task across a diverse array of projects, and eager to learn new skills. Ready to start ASAP
Other Preferred Qualifications:
Prior expertise in some or all of the following:
- DNA/RNA/Protein extraction and quantification, molecular cloning, PCR, RT-PCR, ddPCR assay design and screening, FACS, transfection, CRISPR genome editing, siRNA/shRNA, SDS-PAGE, immunoblotting, cell-based assays, NGS, and viral vector development/use.
- Experience with sequence/data analysis platforms such as Benchling, Snapgene, FlowJo, GraphPad Prism etc. are desirable
Pay Rate Range: $30-45/hr. Salary will be commensurate with experience
Equal Opportunity Employer: We are proud to be an equal opportunity employer. We welcome and encourage applications from all qualified candidates regardless of race, sex, gender identity or expression, disability, age, religion or belief, sexual orientation, or any other characteristic protected by applicable laws and regulations. It is our policy not to discriminate against any applicant or employee, and we are committed to fostering a diverse, inclusive, and respectful work environment across all locations in which we operate. We believe that diversity, equity, and inclusion are fundamental to our mission and enhance our ability to serve clients globally. If you have a disability or require any reasonable accommodations during the application or interview process, please inform your recruiter or contact us directly so that we can explore the appropriate arrangements.
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