Research Associate II
201 Haskins Way, Suite 101, South San Francisco, CA 94080 US
Job Description
- Maintenance of a highly functioning in vivo and ex vivo labs, working with other members of the In Vivo Pharmacology group and other cross-functional scientists.
- Proficient in basic animal handling, including blood sample collection and necropsy with organ/tumor sample collection.
- Setup and execution of in vivo studies using xenograft mouse models of solid tumors including animal preparation/surgery, tumor implantation (s.c., i.p., i.v., or orthotopic), preparation and dosing of therapeutic T cells and other agents via various routes of administration, tracking of tumor growth (eg., bioluminescence/fluorescence, and caliper measurements), collection of blood, tissue, tumor samples, and monitoring of animal health.
- Ex vivo study responsibilities include cell culture, collection and processing of organs and tumor samples for immunological and pathological analysis.
- Collection, entry, analysis, and presentation of study data to project teams.
- Generation and maintenance of electronic lab notebook (ELN) reports, including basic statistical data analysis.
- Data analysis using software packages (FlowJo, FCS Express, Prism).
- Cell therapy experience is ideal, more complex experience a plus.
- Proficient in sterile tissue culture technique and experience working with human cells.
- Experience with flow cytometry assays and analysis.
- Experience in data production.
- Additional specific experience related to the area of focus may be required
- Proficient in executing various xenograft tumor models using immunocompromised and immune-competent mice with adoptive T cell transfer.
- Proficient with mammalian cell culture techniques such as cell line passaging, cryopreservation and cell thawing, and cell counting.
- Proficient using and analyzing high-parameter flow cytometry.
- BSc in biotechnology, molecular biology, microbiology, immunology, oncology or related field with a minimum of 5 years’ experience within the area of focus
- MSc in biotechnology, molecular biology, microbiology, immunology, oncology or related field with a minimum of 3 years’ experience within the area of focus
Pay Rate Range: $40-50/hr depending on experienceÂ
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