Research Scientist
10300 Campus Pointe Drive San Diego, CA 92121 US
Job Description
- Ph.D. in cell biology, immunology, molecular biology, oncology or equivalent field
- Knowledge and experience in using multi-parameter flow cytometry
- Hands-on experience with mammalian cell culture, molecular and cellular technologies (e.g., CRISPR/Cas9 knock-in/out, lentiviral transduction, western blotting, quantitative PCR,) and functional assays (e.g., proliferation, apoptosis, cell cycle) is essential
- Experience in utilizing platforms including IncuCyte, JESS, Flow based cell sorter, ELISA, and MSD in the context of oncology-based drug discovery is a plus
- Utilize and develop multiple disease models to design target validation studies and relevant assays in support of SAR, mechanism of action, mechanisms of resistance, biomarker selection, and disease positioning.
- Develop and implement cell-based assays to address both tumor intrinsic cellular biology and immune-based mechanisms of action for potential drug candidates
- Design and conduct essential mechanistic experiments in cell biology, cellular biochemistry, molecular biology, and assay development
- Accurately maintain written reports and present results in an organized and timely manner.
- Communicate effectively, foster teamwork, and contribute to collaborative efforts.
- Strong commitment to quality and demonstrate adaptability.
- Ph.D. in cell biology, immunology, molecular biology, or equivalent field with 0-2 years of post-doc or industry experience, or M.S. degree with 3+ years of experience, or Bachelors degree with 5+ years of experience in the biopharmaceutical industry developing and optimizing cell-based assays, preferably in Oncology
- Strong background and experience in cancer research with training in molecular and cell biology
- Extensive experience using multi-parameter flow cytometry in the context of primary immune cell isolation and characterization is required.
- Extensive hands-on experience with mammalian cell culture, molecular and cellular technologies (e.g., CRISPR/Cas9 knock-in/out, lentiviral transduction, western blotting, quantitative PCR,) and functional assays (e.g., proliferation, apoptosis, cell cycle) is essential
- Experience in utilizing platforms including IncuCyte, JESS, Flow based cell sorter, ELISA, and MSD in the context of oncology-based drug discovery is a plus.
- Strong record of high-impact and rigorous science though publication history.
- Proficiency in scientific data analysis programs including GraphPad Prism, FlowJo, Microsoft Excel/Powerpoint, is required
- Capability to deliver high quality data in an organized and timely manner
- Ability to work in a fast-paced dynamic team environment; flexibility to adapt to changes with a positive attitude and independently collaborate across teams, requiring excellent communication skills, both written and verbal, with strong interpersonal skills.
The starting hourly compensation for this assignment is a range from $41.82 - $53.12. While the final, individual compensation will be determined by your employer of record (and not client), factors that will be included in making the final determination may include the characteristics of the assignment, such as demonstrated experience, required skill, and the geographic location where the job is performed. The starting hourly compensation may be subject to change.
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