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Research and Development Associate III

Cambridge, MA 2142

Posted: 09/18/2024 Employment Type: Contract Job Category: Scientific Job Number: 614780 Is job remote?: No Country: United States

Job Description


We are seeking a Research and Development Associate III to join the Antibody and Delivery Technologies unit within Biologics Drug Discovery (BDD) team, contributing to our mission to design, optimize, and develop therapeutics to improve the lives of patients with neurodegenerative diseases. In this role, you will work in a lab with a cross-functional team performing experiments where your work will support the development of novel biologics therapeutic approaches to treat CNS and neuromuscular diseases.

What You’ll Do:
• Establish and perform in vivo PK/PD studies for therapeutic proteins, antisense oligonucleotides, viral vectors and other modalities with CNS delivery/targeting properties.
• Perform in vivo immunizations to generate antigen specific antibodies from B cells by next-generation sequencing or hybridoma production
• Contribute to research efforts on specific projects involving novel BBB targets and other modalities
• Perform biochemical and molecular biology assays to enable PK/PD analysis of therapeutic candidate drugs, including ELISA/MSD, and qPCR
• Work as a part of a collaborative and cross-functional team
• Perform data analysis, maintain electronic laboratory notebooks, and present data

Qualifications:
• EDUCATION level BS, MS or Ph.D in Biochemistry, analytical Chemistry or related major.
• Industry experience 3-5 years
• Expertise with in vivo procedures, including injections (IV, SC, IP), blood collection and necropsy/tissue collection (brain, spinal cord, muscle and other tissues)
• Experience with in vivo immunization techniques for antibody generation
• Ability to establish and perform biochemical and molecular assays, including ELISA/MSD, qPCR, BCA and other relevant techniques
• Strong communication, organization and documentation skills
• Quantitative data analysis using GraphPad Prism, MS Office or other relevant software.

Preferred Skills:
• Knowledge in BBB field and CNS delivery technologies including viral-delivery technologies and receptor-mediated transcytosis
• Knowledge of basic neurobiology, neurodegenerative diseases and drug discovery
• Ability to establish and perform biochemical and molecular assays, including FACS and internalization assays using cellular imaging
• Experience with immunohistochemistry, histology and microscopy
• Experience in handling and working with large molecules

Pay ranges between $42-50/hr based on experience 

 

The staffing industry has seen an increase in people falsely representing themselves as recruiters to gather personal information from job seekers. For your safety, do not provide sensitive data to anyone you have not spoken with thoroughly and never provide banking information during the application process. Candidate safety is a top priority at Planet Pharma.

Planet Pharma and The Planet Group of Companies are equal opportunity employers. It is our practice not to discriminate against any employee or applicant based on any criteria, condition or basis protected by laws or regulations in the locations where we do business. All qualified applicants are encouraged to apply. We celebrate diversity and are committed to providing an environment of mutual respect. We believe that diversity, equity and inclusion enable us to better meet our mission and values while serving our clients across the globe. If you have a disability or handicap and would like us to accommodate you in any reasonable way, please inform your recruiter, or contact us, so that we can discuss the appropriate alternatives available.

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About Cambridge, MA

Calling all job seekers! Discover exciting job opportunities in and around Cambridge, Massachusetts, a vibrant city known for its rich history, world-renowned universities like Harvard and MIT, and innovative tech scene. Cambridge offers a unique blend of academic excellence, cultural diversity, and a thriving arts community, with attractions like the iconic Harvard Square, the charming Charles River Esplanade, and the prestigious American Repertory Theater. From savoring local specialties like clam chowder and lobster rolls to cheering on the Red Sox at Fenway Park, there's something for everyone in this dynamic region. Explore job listings today and kick-start your career in this captivating area!

Although this hasn't been an issue at Planet Pharma, the staffing industry has seen an increase in people falsely representing themselves as recruiters to gather personal information from job seekers. For your safety, do not provide sensitive data to anyone you have not spoken with thoroughly and never provide banking information during the application process. Candidate safety is a top priority at Planet Pharma.