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Scientist, Electrophysiology
Job Description
As a member of the research and development team, you will work under the direction of the Senior Director, Molecular and Cellular Biology to optimize and develop pipelines, starting with our chemically induced cellular reprogramming program. This is an exciting interdisciplinary role in a dynamic, rapidly advancing company that will contribute directly to the progression of new therapies as well as the identification of new technologies and disease-modifying therapeutics. DUTIES AND RESPONSIBILITIES:
- Take the lead on assigned R&D initiatives.
- Design, conduct, and optimize electrophysiology and cellular biology experiments to support research and development objectives.
- Conduct experiments in cellular biology and electrophysiology, including but not limited to:
- DNA/RNA extraction, PCR, and qPCR
- Protein expression and analysis (e.g. western blotting, ELISA, flow cytometry)
- Cell culture, transfection, and functional assays
- Single-cell patch-clamp
- Microelectrode assays
- Contribute to the development of complex assays to support drug discovery programs
- Actively contribute to or take a leadership role in cross-functional teams and projects
- Provide training, guidance, and mentorship to junior team members.
- Prepare, review, and refine standard operating procedures (SOPs), experimental plans, and technical reports
- Support research development by ensuring adequate inventory levels of materials and supplies are maintained
- Maintain accurate and detailed laboratory records, including experimental data and observations.
- Operate, maintain, calibrate, and validate essential lab equipment such as biological safety cabinets, incubators, pipet aids, balances, and centrifugation.
- Collaborate with internal and external multidisciplinary teams to achieve pipeline development.
- Ensure compliance with laboratory safety protocols and regulatory guidelines.
- Ability to work a standard schedule and limited weekend work as necessary to complete experiments.
- May perform additional duties as required.
- Degree in Neuroscience, Cellular Biology, or related discipline. PhD and 0~2 years of relevant experience, master’s degree and 5+ years of relevant experience, or bachelor’s degree and 7+ years of relevant research experience, industry preferred.
- Extensive experience in the detailed design, execution, and interpretation of automated and manual patch-clamp electrophysiology studies.
- Experience with HTS electrophysiology platforms such as multielectrode array (MEA) is a plus.
- Proficiency in cell culture techniques, preferred in primary, stem, and differentiated cell types.
- Expertise in cellular biology techniques, such as qPCR, flow cytometry, and HCI.
- Excellent problem-solving skills and ability to interpret and present complex datasets.
- Organized, detail-oriented, and excellent record-keeping skills.
- Knowledge of experimental design and statistical analysis tools (e.g., GraphPad Prism, JMP)
- Excellent written and verbal communication skills.
- Prove ability to manage multiple tasks and prioritize assignments.
- Ability to work independently with direction and perform well in a team environment
Equal Opportunity Employer: We are proud to be an equal opportunity employer. We welcome and encourage applications from all qualified candidates regardless of race, sex, gender identity or expression, disability, age, religion or belief, sexual orientation, or any other characteristic protected by applicable laws and regulations. It is our policy not to discriminate against any applicant or employee, and we are committed to fostering a diverse, inclusive, and respectful work environment across all locations in which we operate. We believe that diversity, equity, and inclusion are fundamental to our mission and enhance our ability to serve clients globally. If you have a disability or require any reasonable accommodations during the application or interview process, please inform your recruiter or contact us directly so that we can explore the appropriate arrangements.
Fraud Alert: Candidate safety is a top priority at Planet Pharma. The industry has seen an increase in people falsely representing themselves as recruiters to gather personal information from job seekers. For your safety, do not provide sensitive data to anyone you have not spoken with thoroughly, never provide banking information during the application process and always double check the email address of the Recruiter to ensure it’s from an official Planet Pharma domain (@planet-pharma.com, @planet-pharma.co.uk, and @ppgadvisorypartners.com) and not a domain with an alternative extension like .net, .org or .jobs.
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