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Scientist, Preformulation

Cambridge, MA 02139

Posted: 10/10/2024 Employment Type: Contract Job Category: Scientific Job Number: 615024 Is job remote?: No Country: United States

Job Description

Job Summary:
The company is seeking an exceptional candidate to contribute to preformulation research in a small, fast-paced and highly collaborative team. This contract position resides within the Formulations Sciences group of Pharmaceutical Sciences. The candidate will work full time onsite and contribute to the execution of laboratory activities related to the transition of novel small molecule compounds from Discovery into Development in support of the company's  pre-clinical and clinical programs. An ideal candidate will have a strong foundation in analytical techniques such as UPLC/HPLC (Empower proficiency) and an understanding of early drug development processes and experiments. Experience in preformulation development and physicochemical characterization is highly desired, however not required.
An ideal candidate would have approximately 2+ years’ experience working in pharmaceutical sciences (preformulation, analytical or formulation development).
Responsibilities:
  • Prepare buffers and common lab solutions
  • Execution of analytical experiments with XRPD, DSC, TGA, DVS, SEM, optical microscopy and UPLC/HPLC (Empower)
  • Screen excipients/formulation vehicles for solubility and stability to optimize preclinical formulations to enable non-GLP and GLP pre-clinical studies
  • Perform drug substance and formulation stability studies to ensure optimal formulation design
  • Coordinate vehicle/formulation preparations for in vivo studies
  • Execute dissolution studies (Distek and Pion µDISS) to support formulation development and FIH development
  • Maintain an accurate, timely, and compliant laboratory notebook

Qualifications:
  • B.S. degree in chemistry, analytical chemistry, pharmaceutics, chemical engineering or material sciences
  • 2+ years’ experience working in pharmaceutical sciences (preformulation, analytical or formulation development)
  • Experience in the Discovery and Development interface [desirable not required]
  • Experience working with common excipients and volumetric glassware
  • Proficiency with UPLC/HPLC and Empower Software
  • Some knowledge of and interest in learning more about small molecule and pre-clinical formulation development

Capabilities:
  • Ability to effectively prioritize and manage multiple tasks and compounds
  • Self-motivated and willing to “learn on the job” and ask for assistance when needed
  • At home in a results-driven, highly accountable environment where you can make a clear impact
  • A team player, who listens effectively and invites response and discussion
  • A collaborator who communicates in an open, clear, complete, timely and consistent manner

The staffing industry has seen an increase in people falsely representing themselves as recruiters to gather personal information from job seekers. For your safety, do not provide sensitive data to anyone you have not spoken with thoroughly and never provide banking information during the application process. Candidate safety is a top priority at Planet Pharma.

Planet Pharma and The Planet Group of Companies are equal opportunity employers. It is our practice not to discriminate against any employee or applicant based on any criteria, condition or basis protected by laws or regulations in the locations where we do business. All qualified applicants are encouraged to apply. We celebrate diversity and are committed to providing an environment of mutual respect. We believe that diversity, equity and inclusion enable us to better meet our mission and values while serving our clients across the globe. If you have a disability or handicap and would like us to accommodate you in any reasonable way, please inform your recruiter, or contact us, so that we can discuss the appropriate alternatives available.

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About Cambridge, MA

Calling all job seekers! Discover exciting job opportunities in and around Cambridge, Massachusetts, a vibrant city known for its rich history, world-renowned universities like Harvard and MIT, and innovative tech scene. Cambridge offers a unique blend of academic excellence, cultural diversity, and a thriving arts community, with attractions like the iconic Harvard Square, the charming Charles River Esplanade, and the prestigious American Repertory Theater. From savoring local specialties like clam chowder and lobster rolls to cheering on the Red Sox at Fenway Park, there's something for everyone in this dynamic region. Explore job listings today and kick-start your career in this captivating area!

Although this hasn't been an issue at Planet Pharma, the staffing industry has seen an increase in people falsely representing themselves as recruiters to gather personal information from job seekers. For your safety, do not provide sensitive data to anyone you have not spoken with thoroughly and never provide banking information during the application process. Candidate safety is a top priority at Planet Pharma.