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Scientist, Preformulation
45 Sidney Street Cambridge, MA 02139 US
Job Description
The company is seeking an exceptional candidate to contribute to preformulation research in a small, fast-paced and highly collaborative team. This contract position resides within the Formulations Sciences group of Pharmaceutical Sciences. The candidate will work full time onsite and contribute to the execution of laboratory activities related to the transition of novel small molecule compounds from Discovery into Development in support of the company's pre-clinical and clinical programs. An ideal candidate will have a strong foundation in analytical techniques such as UPLC/HPLC (Empower proficiency) and an understanding of early drug development processes and experiments. Experience in preformulation development and physicochemical characterization is highly desired, however not required.
An ideal candidate would have approximately 0-3 years’ experience working in pharmaceutical sciences (preformulation, analytical or formulation development).
Responsibilities:
- Prepare buffers and common lab solutions
- Execution of analytical experiments with XRPD, DSC, TGA, DVS, SEM, optical microscopy and UPLC/HPLC (Empower)
- Screen excipients/formulation vehicles for solubility and stability to optimize preclinical formulations to enable non-GLP and GLP pre-clinical studies
- Perform drug substance and formulation stability studies to ensure optimal formulation design
- Coordinate vehicle/formulation preparations for in vivo studies
- Execute dissolution studies (Distek and Pion µDISS) to support formulation development and FIH development
- Maintain an accurate, timely, and compliant laboratory notebook
Qualifications:
- B.S. degree in chemistry, analytical chemistry, pharmaceutics, chemical engineering or material sciences
- 0-3 years’ experience working in pharmaceutical sciences (preformulation, analytical or formulation development)
- Experience in the Discovery and Development interface [desirable not required]
- Experience working with common excipients and volumetric glassware
- Proficiency with UPLC/HPLC and Empower Software
- Some knowledge of and interest in learning more about small molecule and pre-clinical formulation development
Capabilities:
- Ability to effectively prioritize and manage multiple tasks and compounds
- Self-motivated and willing to “learn on the job” and ask for assistance when needed
- At home in a results-driven, highly accountable environment where you can make a clear impact
- A team player, who listens effectively and invites response and discussion
- A collaborator who communicates in an open, clear, complete, timely and consistent manner
Equal Opportunity Employer: We are proud to be an equal opportunity employer. We welcome and encourage applications from all qualified candidates regardless of race, sex, gender identity or expression, disability, age, religion or belief, sexual orientation, or any other characteristic protected by applicable laws and regulations. It is our policy not to discriminate against any applicant or employee, and we are committed to fostering a diverse, inclusive, and respectful work environment across all locations in which we operate. We believe that diversity, equity, and inclusion are fundamental to our mission and enhance our ability to serve clients globally. If you have a disability or require any reasonable accommodations during the application or interview process, please inform your recruiter or contact us directly so that we can explore the appropriate arrangements.
Fraud Alert: Candidate safety is a top priority at Planet Pharma. The industry has seen an increase in people falsely representing themselves as recruiters to gather personal information from job seekers. For your safety, do not provide sensitive data to anyone you have not spoken with thoroughly, never provide banking information during the application process and always double check the email address of the Recruiter to ensure it’s from an official Planet Pharma domain (@planet-pharma.com, @planet-pharma.co.uk, and @ppgadvisorypartners.com) and not a domain with an alternative extension like .net, .org or .jobs.
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