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Scientist - II (Associate)
33 Avenue Louis Pasteur Boston, MA 02115 US
Job Description
Target Pay Rate: 35-44.30/hr **salary will be commensurate with experience
Job Description:
Client is a global health care leader with a diversified portfolio of prescription medicines, vaccines, and animal health products. The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where client has codified its legacy for over a century. Client's success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare.
Early Biologics Characterization - Boston Research Laboratories (MRL) is seeking a contractor to execute on existing protein analytics workflows. Specifically, to perform intact MS, peptide mapping and other biophysical assays such as SEC, HIC, CE-SDS, DSF, DLS, Buffer Exchange.
In this role you will build and then use a combination of skills to help with the biologics characterization workflow. Additional laboratory automation skills are desired but not required. This role will require an eagerness to learn and an ability to work with different teams and different equipment to operate a robust characterization platform. Your efforts will be a complement and core resource to existing capabilities and will serve to expand the teams ability to interrogate biologics diversity to identify optimal leads. You will have the opportunity to apply your enthusiasm and technical skills as a member of Discovery Biologics - Boston to support and help drive multidisciplinary biotherapeutic discovery programs.
Responsibilities:
1. Operate and maintain existing mass spectrometry platforms and implement new workflows for protein characterization
2. Perform LC-MS data analysis using various software and bioinformatic tools to elucidate the quality attributes of therapeutics proteins and other novel modalities.
3. Troubleshoot automation methods and devices to maintain optimal high throughput protein analyses
4. Generate frequent characterization summary reports.
5. Follow and improve Standard Operating Procedures for biologics characterization workflows.
Qualifications:
• A minimum of a B.S in a relevant field (e.g. protein sciences, chemical or bioengineering, biochemistry or similar) with additional training being desirable. Experience: • BS with 6+ years of experience/MS with 4+years./PHD with 1-3years. • Industry experience is preferred. Required experience and skills: • Experience with mass spectrometry and other biophysical assays workflows and their inherent data management. • Knowledge and hands on experience in LC-MS based sample preparation for proteins • Strong problem solving and communication skills. • Ability to multitask, time management, and prioritize activities. Preferred experience and skills: • Experience with operating high resolution MS instruments such as Agilent Q-TOF, Thermo Orbitraps (e.g. QE+, QE-HF, Exploris 480) and liquid handling platforms such as Vanquish, Acquity UPLC. • Experience analyzing data with BioPharma finder, BioConfirm and other MS software is a plus • Experience with EMPOWER is a plus • ELN knowledge is desirable Note: • 100% onsite role.
Equal Opportunity Employer: We are proud to be an equal opportunity employer. We welcome and encourage applications from all qualified candidates regardless of race, sex, gender identity or expression, disability, age, religion or belief, sexual orientation, or any other characteristic protected by applicable laws and regulations. It is our policy not to discriminate against any applicant or employee, and we are committed to fostering a diverse, inclusive, and respectful work environment across all locations in which we operate. We believe that diversity, equity, and inclusion are fundamental to our mission and enhance our ability to serve clients globally. If you have a disability or require any reasonable accommodations during the application or interview process, please inform your recruiter or contact us directly so that we can explore the appropriate arrangements.
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