Scientist - III (Senior) - MA Only
4 Bent Street East Cambridge, MA 02141 US
Our Genome Sciences (GS) Neuro-Immunology iPSC disease modeling group within the Department of Data and Genome Sciences (DGS) collaborates with multiple therapeutic areas (Immunology and Neuroscience) to identify and validate new targets based on Human Genetics. Our mission is to validate targets through development and application of improved human model systems to better understand each targets mechanism of action. Our group utilizes genetic (CRISPR) and pharmacological manipulations of induced pluripotent stem cell (iPSC) model systems to validate the role of targets in mechanisms related to pathobiology of human diseases.
The Genome Sciences Neuro-Immunology iPSC disease modeling group is seeking a passionate and dedicated experimental biologist or pharmacologist to join our team. In collaboration with DGS and pharmacology colleagues, the candidate will help develop automation protocols for high-throughput screening to identify neuroimmune drug targets. You will be part of a dynamic and challenging early discovery research environment that is based at our Research Labs in Cambridge, MA. The Scientist will report into the GS Neuro-Immunology iPSC disease modeling group lead and will be expected to work both independently and collaboratively with colleagues.
The responsibilities of this Scientist role include but are not limited to:
- Formulate and execute automation protocols to enable high throughput assay readouts with iPSC-derived microglial cells in collaboration with experimental scientists within and outside DGS.
- Work with cross-functional teams including disease area biologists, pharmacologists and chemists to execute high throughput screens and identify neuroimmune drug targets.
- Effectively communicate and present data to diverse group of scientists including senior managers.
• Candidate with BS/MS with 8+ or PhD with 2+ years of experience in molecular/cellular biology or related biological fields.
• Possess excellent communication skills with ability to clear present scientific data and project updates to a diverse group of scientists.
• Experience working in collaborative research environments to advance scientific projects.
• Experience with human stem cell culture, genetic/genomic manipulations (CRISPR), and automation applied to high throughput screening approaches are needed.
• Previous experience working on drug discovery projects.
• Experience in the field of Neuroscience or Immunology.
Preferred/Nice to haves:
• Functional assay development
• FLOW/FACS experience
• Team Player
• Willing to ask questions
• Excellent communication skills
• Individual contributor
Pay Range: 30-45/hr
Salary will be commensurate with experience
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