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Scientist - III (Senior) - MA Only

East Cambridge, MA 02141

Posted: 02/15/2024 Employment Type: Contract Job Category: Scientific Job Number: 547048 Is job remote?: No Country: United States

Job Description

We are seeking a highly motivated Contract Research Scientist to join our Chemical Biology Department. The successful candidate will support Mass Spectrometry-based proteomics workflows for target identification and validation, working closely with proteomics scientists and colleagues in Chemistry, Pharmacology and Disease Area Biology functions to identify and quantify proteins from biologically relevant tissues, organs and cells. We seek people inspired by our mission that will fit well with the collaborative, rigorous and entrepreneurial spirit of our company culture.


• MS/BS degree with a minimum of 3-5 years of hands-on lab-based experience in mammalian cell culture, 96-well plate assays, Western Blotting and protein biochemistry is required.
• The ideal candidate will be highly skilled in mammalian cell culture (at least 2 years of experience) to support: 1) culturing of diverse primary and cancer cell lines using different labware (from multi-layer flasks to 96-well plates); 2) Western Blot assays; 3) protein extraction and quantification from cell lines and tissues.
• Hands-on experience adapting, optimizing and/or developing multi-well assays (including compound treatment of cells in a 96-well format), prior experience with liquid handlers, sub-cellular fractionation and tissue homogenization protocols are preferred.
• Familiarity with chemical labeling techniques and mass spectrometry sample preparation workflows such as in-solution digestion and HPLC-based fractionation is highly desirable.

• The ideal candidate should be have excellent communication skills and ability to collaborate closely with scientists within the team to adapt and optimize workflows.
• The candidate is expected to work well in a team environment and contribute to the team deliverables with strong problem-solving skills, laboratory skills and exquisite attention to experimental details and record keeping.

Pay Range: 38-48/hr
Salary will be commensurate with experience
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About East Cambridge, MA

Explore exciting job opportunities in the vibrant area of East Cambridge, Massachusetts! Nestled in the heart of the Greater Boston area, East Cambridge offers a bustling tech hub, renowned universities, and a rich historical charm. With landmarks like the iconic Charles River, world-class museums including the Museum of Science, and acclaimed theaters such as the American Repertory Theater, this area truly has something for everyone. Discover career growth in this dynamic community filled with unique culture, delectable cuisine, and endless entertainment options. Begin your journey towards an exciting career in East Cambridge today!

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