Scientist - III (Senior)
213 East Grand Avenue South San Francisco, CA 94080 US
Job Description
Job Description:
Scientist, Protein Characterization
The Protein Sciences Department within the Discovery Biologics organization in South San Francisco is seeking an experienced Scientist to join the Protein Characterization & Developability team.
The Characterization and Developability team works integrated with other teams within Protein Sciences Department as well as
Therapeutic Area discovery project teams and plays a pivotal role in early biologics discovery by engaging in high throughput biophysical screening, molecule optimization and
Developability assessments to enable selection of the best candidate molecule for further development.
The successful candidate is expected to have experience in protein chemistry and biophysical characterization of biologics using a variety of analytical tools -
chromatographic, electrophoretic, light scattering and other analytical methods.
The ideal candidate will have hands-on experience in characterization of monoclonal antibodies (mAbs), bi-/multi-specifics, fusion proteins, antibody drug conjugates (ADCs)
Qualifications: Education Requirement: • BS/BA degree in Biophysics/Biochemistry or related field with 4+ years of relevant experience or MS degree in Biophysics/Biochemistry or related field with 2+ years of relevant experience. Experience and Skills: • Hands-on expertise in analytical characterization of proteins using a wide range of physicochemical characterization methods such as SEC, SEC-MALS, HIC, CE-SDS, cIEF, DLS/SLS, DSF, etc. • Strong understanding of protein structure, biophysics, and analytical mindset to enable understanding of the relation between physicochemical properties and proteins structure/sequences • Previous experience with analytical characterization and developability assessment of biologics highly desired • Experience/Interest with high-throughput analytical characterization workflows • Strong analytical skills and attention to detail • Ability to work on multiple projects and ability to meet aggressive timelines • Documentation of procedures, methods, data, and results in electronic laboratory notebooks • Team player and excellent interpersonal skills • Strong communication and presentation skills Software: Basic MS office skills. Experience with Electronic laboratory notebook would be nice to have
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