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Scientist 1 (Protein Expression and Purification, Contract role)

S San Francisco, CA 94080

Posted: 06/18/2024 Employment Type: Contract Job Category: Scientific Job Number: 606612 Is job remote?: No Country: United States

Job Description


Description The departments of BioMolecular Research and Structural Biology, within the Protein Sciences organization are looking for a versatile, dynamic, self-motivated individual to join us as a Scientist 1. The selected individual will contribute towards recombinant protein expression and purification efforts to support drug discovery activities. This role will facilitate expression analysis of novel protein encoding constructs, by building, developing and utilizing automated high throughput processes for expression, purification and characterization for research and portfolio projects. The qualified candidate must be technically strong, self- driven, passionate about science, results and detail oriented. In this collaborative role, the successful candidate will have the opportunity to work with other scientists and group leaders within and outside our department to fulfill protein production needs. This is an on-site role based in South San Francisco, CA.

Job Responsibilities
  • Protein purification using a variety of chromatographic techniques (affinity, size exclusion, ion exchange) for structural and biochemical studies
  • Screening and optimizing expression and purification of challenging membrane proteins using detergent lysis
  • Using various expression platforms such as E.coli, insect cells (BEVS), and mammalian expression platforms for small and medium scale protein production
  • Performing SDS-PAGE, western blot, protein characterization assays by different biophysical and biochemical methods
  • Operating and maintaining High performance liquid chromatography systems (HPLC) for protein purification and analysis
  • Performing gel analysis, capturing and interpreting data, uploading results to LIMS databases and sharing with stakeholders
  • Communicating with and presenting to collaborators and stakeholders across the Protein Sciences organization
Required qualifications
  • Applicants with a Masters degree in the Biological Sciences should have at least 3-4 years of scientific experience and applicants with a PhD degree (Biochemistry, Biophysics, Cell Biology, Molecular Biology) should have at least 1-2 years of relevant experience
  • Strong protein purification expertise in affinity and size exclusion chromatography
  • Strong aseptic cell culture techniques for handling routinely insect and mammalian cells
  • Ability to think critically, analyze results, plan experiments and carry out troubleshooting as needed
  • Strong desire to learn new techniques, advance technologies related to protein optimization and interest in implementing new expression systems.
  • Demonstrated ability to work independently in a team-oriented setting
  • Expertise with automation and high-throughput process development will be a plus
  • Excellent verbal and written communication skills
  • Excellent organizational skills



Pay Rate Range: $45-52/hr. Salary will be commensurate with experience 

The staffing industry has seen an increase in people falsely representing themselves as recruiters to gather personal information from job seekers. For your safety, do not provide sensitive data to anyone you have not spoken with thoroughly and never provide banking information during the application process. Candidate safety is a top priority at Planet Pharma.

Planet Pharma and The Planet Group of Companies are equal opportunity employers. It is our practice not to discriminate against any employee or applicant based on any criteria, condition or basis protected by laws or regulations in the locations where we do business. All qualified applicants are encouraged to apply. We celebrate diversity and are committed to providing an environment of mutual respect. We believe that diversity, equity and inclusion enable us to better meet our mission and values while serving our clients across the globe. If you have a disability or handicap and would like us to accommodate you in any reasonable way, please inform your recruiter, or contact us, so that we can discuss the appropriate alternatives available.

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About S San Francisco, CA

Ready to find your dream job in the vibrant area around South San Francisco, California? This bustling region, nestled in the heart of the Bay Area, offers an array of unique benefits and growth opportunities for job seekers. With its proximity to iconic landmarks like the Golden Gate Bridge and Alcatraz Island, a thriving culinary scene featuring local favorites like clam chowder bread bowls at Fisherman's Wharf, and a rich cultural tapestry showcased in renowned art galleries like the San Francisco Museum of Modern Art, there is no shortage of reasons to kickstart your career here. Explore our job listings today and discover why pursuing your career in this enchanting region is the perfect choice for your professional growth and personal fulfillment.

Although this hasn't been an issue at Planet Pharma, the staffing industry has seen an increase in people falsely representing themselves as recruiters to gather personal information from job seekers. For your safety, do not provide sensitive data to anyone you have not spoken with thoroughly and never provide banking information during the application process. Candidate safety is a top priority at Planet Pharma.