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Scientist 1 Bioconjugation Chemistry

San Rafael, CA 94901

Posted: 09/10/2024 Employment Type: Contract Job Category: Scientific Job Number: 614197 Is job remote?: No Country: United States

Job Description

Duties:
  • Synthesis, optimization, and high-quality delivery of various polymer, protein/peptide, and lipidated bioconjugates in support of discovery and development of novel therapeutics, with an emphasis on oligonucleotides
  • Development and implementation of new linker chemistries/spacers and bioconjugation methods for targeted drug delivery
  • Leveraging appropriate purification and analytical characterization approaches for QC and validation
  • Collaboration with internal and external partners for material transfer to support in vitro and in vivo POC experiments; assemble data packages and maintain quality control documentation through Benchling for final product delivery.
  • Effectively partner with cross-functional teams, sharing insights, troubleshooting issues, and driving science forward from the bench
  • Serve independently as bioconjugation technical lead and subject matter expert for internal and external project communications
  • Perform data analysis, interpret, and present results during internal and external meetings; attend and participate in scientific proceedings.
  • Prepare and optimize chemistry SOPs
  • Participate and present data and share responsibility for project milestones
Requirements:
  • Ph.D. in Chemical Engineering, Chemical Biology, Chemistry, or related fields is required; Scientist 1 will have 0-2 years of industry/post-doc experience relating to drug development
  • Strong foundation in macromolecular chemistry, bioconjugation, analytical chemistry and/or chemical biology is strongly desired.
  • A record of accomplishments/publications in relevant scientific discipline and some hands-on experience in oligonucleotide delivery is preferred but not required.
  • Extensive experience with different bioconjugation strategies and optimizations thereof for polymers, proteins/peptides, lipids, oligonucleotides and other biomolecules
  • In-depth experience in bioconjugate purification techniques including various liquid chromatography methods (e.g. RP, IEX, SEC, HIC, affinity, FPLC) and membrane filtrations (e.g. TFF)
  • Prior experience in biochemistry techniques and analytical methods such as SEC-MALs, LCMS, SPR/BLI, ELISA, SDS-PAGE, enzyme activity assays, etc.
  • Willingness to learn new bioconjugation chemistries or delivery modalities and work across diverse therapeutic areas to develop protein therapeutics.
  • Strong analytical mindset and chemistry problem-solving with creative thinking
  • The position requires organization skills, attention to detail, self-motivation, and strong teamwork in a fast-paced setting

The staffing industry has seen an increase in people falsely representing themselves as recruiters to gather personal information from job seekers. For your safety, do not provide sensitive data to anyone you have not spoken with thoroughly and never provide banking information during the application process. Candidate safety is a top priority at Planet Pharma.

Planet Pharma and The Planet Group of Companies are equal opportunity employers. It is our practice not to discriminate against any employee or applicant based on any criteria, condition or basis protected by laws or regulations in the locations where we do business. All qualified applicants are encouraged to apply. We celebrate diversity and are committed to providing an environment of mutual respect. We believe that diversity, equity and inclusion enable us to better meet our mission and values while serving our clients across the globe. If you have a disability or handicap and would like us to accommodate you in any reasonable way, please inform your recruiter, or contact us, so that we can discuss the appropriate alternatives available.

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About San Rafael, CA

Ready to take the next step in your career? Explore our job opportunities in the vibrant San Rafael, California area! Nestled in Marin County, San Rafael offers a perfect blend of picturesque landscapes, cultural attractions such as the Marin Veterans' Memorial Auditorium and the Marin History Museum, and a thriving culinary scene with diverse eateries like Sol Food and Terrapin Crossroads. This charming city also boasts easy access to outdoor adventures at China Camp State Park and opportunities to appreciate local art at the Falkirk Cultural Center. Join us in San Rafael, where career growth meets undeniable charm – apply now and discover your next career move in this dynamic region!

Although this hasn't been an issue at Planet Pharma, the staffing industry has seen an increase in people falsely representing themselves as recruiters to gather personal information from job seekers. For your safety, do not provide sensitive data to anyone you have not spoken with thoroughly and never provide banking information during the application process. Candidate safety is a top priority at Planet Pharma.