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Scientist I - Structural Biology - Contractor

Redwood City, CA 94063

Posted: 12/20/2024 Employment Type: Contract To Hire Job Category: Scientific Job Number: 616556 Is job remote?: No Country: United States

Job Description


Scientist I - Structural Biology - Contractor 

The Opportunity:


We are looking for a Scientist I to join the Structural Biology (X-Ray Crystallography) team and support multiple oncology therapeutic programs, mostly through generation of protein crystal structures. Working from the bench, they will apply their expertise in protein purification, identification and optimization of crystallization conditions, and routine production and harvesting of co-crystals of protein and small molecules.


Required Experience, Skills, and Education:

  • Ph.D + 2 years of experience in Biotech/Pharma

  • Experience with protein handling, characterization, and storage (FPLC or HPLC techniques like SEC and affinity chromatography. PAGE, quantitation via Bradford and nanodrop etc.).

  • Experience with growing and harvesting protein crystals highly desirable. Prior use of crystallographic software suites (CCP4, Phenix) and visualization software (PyMOL, Chimera) also highly desirable.

  • Experience with protein-protein complexes including antibodies/Fabs, molecular glues, PROTACs, etc.

  • Demonstrated ability to follow written protocols and document research progress.

  • Rigorous, quantitative, detail-oriented experimentalist.

  • Excellent written and verbal communication skills.

  • Conscientious team-player interested in a fast-paced biotech environment.

  • Demonstrated willingness to learn and improve processes.

Preferred Skills:

  • Experience with biophysical characterization such as MS, Thermal Shift Analysis, SPR a plus.

  • Experience with protein-ligand crystallization and refinement

  • Experience in protein expression including construct design and protein engineering.
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About Redwood City, CA

Ready to embark on an exciting career opportunity in the vibrant area around Redwood City, California? Nestled in the heart of Silicon Valley, this thriving region offers a perfect blend of innovation, growth, and charm. From the bustling tech scene to the serene beauty of Redwood City's parks, like Edgewood Park and Pulgas Ridge Preserve, there's something here for everyone. Immerse yourself in the local culture by visiting the Fox Theatre or exploring art galleries like The Art Center and Redwood City Art Kiosk. With a bustling food scene offering everything from trendy cafes to authentic Mexican cuisine, it's no wonder that Redwood City is a top choice for job seekers looking to thrive in a dynamic environment. Browse our job listings today and take the next step towards a fulfilling career in this captivating locale!

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