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Scientist I/II

South San Francisco, CA 94080

Posted: 03/01/2024 Employment Type: Contract Job Category: Scientific Job Number: 597627 Is job remote?: No Country: United States

Job Description


Target PR Range: 32-56/hr
*Depending on experience

General Position Summary/Purpose:

The Quantitative Translational ADME Science (QTAS) department is seeking a highly motivated ADME/DMPK Scientist contractor (6 months) to join the In Vitro ADME Science group (Uptake Transporter Center of Excellence). The successful candidate will work in collaboration with other team members to characterize the ADME properties of candidate drug molecules. QTAS works very closely with other disciplines (medicinal chemistry, pharmaceutical sciences, pharmacology, toxicology etc.) to conduct preclinical studies, support clinical evaluation and contribute to IND and NDA filings.

In this role, you will be a scientist with hands-on experience for routinely managing mammalian cells, hepatocytes-based drug transporter assays to characterize pipeline candidate in a state-of-the art facility.

Key Accountabilities/Core Job Responsibilities:

· Routine mammalian cell culture and preservation in an efficient manner

· Handling and seeding of primary hepatocytes and recombinant cells

· Conducting HT-screening for inhibition potential on uptake transporters

· Conducting in vitro ADME/drug-drug interactions studies

· Analyzing data and maintenance of detailed, accurate and comprehensible study documentations

 

Qualifications

Education, Qualifications and Experience Requirements (degree, certifications, etc.):

· MS degree (+0 years of experience),

· B.S. (5+ years of experience) -in pharmaceutical sciences, pharmacology, biological chemistry or equivalent in drug metabolism or related discipline with relevant industry experience in drug discovery/development

· (Candidates with PhD/PharmD degree (0+ years of experience), MS degree (+3 years of experience)

· Excellent skills and understanding of recombinant/transiently transfected cell lines, culture, seeding, storage is must

· Working experience with hepatocytes, 2D/3D culture

· Hands-on-experience with molecular and cellular biology laboratory techniques

· Working experience with in vitro drug transporters, metabolism is a plus

· Familiarity with enzyme/transporter kinetics, data fitting

· Experience with radioisotope-based assay is a plus

· Knowledge of both biological and physicochemical properties of small molecules that influence ADME

· Experience with use of electronic lab notebook is a plus

· The individual is also expected to be organized, a team player, passionate about drug discovery, and possess effective communication skills

The staffing industry has seen an increase in people falsely representing themselves as recruiters to gather personal information from job seekers. For your safety, do not provide sensitive data to anyone you have not spoken with thoroughly and never provide banking information during the application process. Candidate safety is a top priority at Planet Pharma.

Planet Pharma and The Planet Group of Companies are equal opportunity employers. It is our practice not to discriminate against any employee or applicant based on any criteria, condition or basis protected by laws or regulations in the locations where we do business. All qualified applicants are encouraged to apply. We celebrate diversity and are committed to providing an environment of mutual respect. We believe that diversity, equity and inclusion enable us to better meet our mission and values while serving our clients across the globe. If you have a disability or handicap and would like us to accommodate you in any reasonable way, please inform your recruiter, or contact us, so that we can discuss the appropriate alternatives available.

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About South San Francisco, CA

Ready to take the next step in your career journey? Explore our job opportunities in the vibrant area surrounding South San Francisco, California! Known for its proximity to the iconic Golden Gate Bridge and the bustling tech hub of Silicon Valley, this region offers unrivaled growth potential and a dynamic work environment. With a unique blend of culture, including the renowned SFMOMA art museum, the lively Castro District, and delectable cuisine like the famous sourdough bread at Boudin Bakery, South San Francisco is the perfect place to thrive professionally while enjoying the beauty of nearby parks like Golden Gate Park and the breathtaking views of the Pacific Ocean. Join us in discovering the endless possibilities for your career in this enchanting region!

Although this hasn't been an issue at Planet Pharma, the staffing industry has seen an increase in people falsely representing themselves as recruiters to gather personal information from job seekers. For your safety, do not provide sensitive data to anyone you have not spoken with thoroughly and never provide banking information during the application process. Candidate safety is a top priority at Planet Pharma.