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Scientist I

North Chicago, IL 60064

Posted: 06/25/2024 Employment Type: Contract Job Category: Scientific Job Number: 609391 Is job remote?: No Country: United States

Job Description


Target PR Range: 24-34/hr
*Depending on experience

Quantitative, Translational & ADME Sciences Department has an open position for a Scientist I position in North Chicago, IL. The successful candidate will be responsible for non-regulated quantitative LC-MS/MS bioanalysis of small molecules from in vivo and in vitro samples, including extraction, data analysis and interpretation.

Key Responsibilities Include:
• Use liquid handling robotics.
• Perform quantitative LC-MS/MS (Liquid Chromatography Mass Spectrometry) analysis of small molecules from various bio-matrices in vivo and in vitro to support PK/PD, ADME, efficacy, and exploratory toxicology studies.
• Basic Operation and troubleshooting of AB Sciex LC-MS/MS systems.
• Maintain excellent documentation of all work including LIMS, test methods, and protocols.
• Work closely with multiple teams across Discovery and DMPK-BA to support bioanalysis.

Qualifications:
• B.S. in analytical chemistry or related field years of relevant academic/pharmaceutical industry experience.
• Knowledge of protein precipitation, liquid/liquid extraction, and solid phase extraction.
• Ability to operate and troubleshoot HPLCs, Leap/CTC PAL autosamplers and triple quad mass spectrometers.
• Experience with quantitative bioanalysis of small molecules.
• Knowledge of chromatographic and analytical methodologies.
• The ideal candidate is detail oriented and committed to generating high-quality results within tight deadlines and across different projects.
• Proven ability to work independently or under minimal supervision in a high-throughput environment to design and conduct experiments, interpret, document, and communicate results, as well as in a team environment to collaborate successfully across other groups within R&D.
• Strong communication, interpersonal, and presentation skills.

• Experience operating and troubleshooting current LC-MS/MS platforms (Agilent HPLCs, Leap/CTC PAL and ADDA autosamplers, Sciex API-5500/6500 triple quad Mass Spectrometers) and software (e.g. Discovery Quant, Analyst, Electronic notebook) is highly preferred.

Key Leadership Competencies:
• Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance.
• Learns fast, grasps the "essence" and can change course quickly where indicated.
• Raises the bar and is never satisfied with the status quo.
• Creates a learning environment, open to suggestions and experimentation for improvement.
• Embraces the ideas of others, nurtures innovation and manages innovation to reality


 
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