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Scientist II

Worcester, MA 01605

Posted: 01/14/2025 Employment Type: Contract Job Category: Scientific Job Number: 616539 Is job remote?: No Country: United States

Job Description


Target PR Range: 35-45/hr
*Depending on experience

Job Description: Scientist (Contractor) in Genetic Medicine

The Biotherapeutics and Genetics Medicine department within Discovery Research is seeking a highly motivated research scientist to join in the Genetic Medicine (GM) group at Company Bioresearch Center (ABC). The ABC site, based in Worcester, MA, offers a unique setting where GM, Biologics drug discovery, development and manufacturing coexist in one location. Our team interacts with multidisciplinary groups across Company focused on developing therapies for Immunology, Neurology, Ophthalmology and Oncology diseases.

As an integral member of the GM team this individual will perform research related to mRNA therapeutics to strength the platform and support various programs. The successful candidate is expected to have knowledge of RNA molecular biology, production, quality control, and cell-based assays. As one of the key team members, this individual will work with scientists across different functional groups and therapeutic areas to discover and develop next generation biologics through interrogation of RNA-related technologies.

Key Responsibilities:
· In vitro transcription to produce mRNA at different scales to support the platform development and therapeutic programs.
· RNA Purification using affinity chromatography (AKTA) and other strategies for purification.
· Quality control assays for mRNAs like electrophoresis, ELISA, qPCR, etc.
· Perform cell-based assays, such as cell culture, transfection, and flow cytometry.
· Work closely with the manager and cross-functional team members on multiple tasks with the ability to analyze, interpret, and present data.
· Assist in ordering reagents from internal and external suppliers and communicating with CROs.
· Generate reliable and reproducible data in a timely manner. Read and adapt scientific literature to accomplish assignments. Demonstrate broad and versatile technical expertise within discipline.
· Maintain electronic laboratory notebooks (ELN) in compliance with the Company Laboratory Notebook Policy.
· Stay updated and in compliance on all departmental and corporate training.

Key Qualifications:
· MS in molecular biology, biochemistry, biomedical engineering or related field with 0-2 years of experience in biotherapeutics or genetic medicine or BS with a minimum of 3-5 years of relevant industry experience.
· Hands-on experience with nucleic acid preparation, purification (AKTA), QC, and cell-based assays.
· Working knowledge of related tools/software (SnapGene, Prism, FlowJo, Excel, PowerPoint etc.).
· Self-motivated, hard-working, detail-oriented, resourceful, and able to work in a fast-paced team environment with demonstrated problem-solving skills.
· High-quality written and oral communication skills and the ability to excel in a collaborative environment.
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About Worcester, MA

Ready to discover exciting job opportunities in the vibrant city of Worcester, Massachusetts? Join us in exploring a region brimming with growth potential and unique charm. From the majestic Worcester Art Museum to the exhilarating performances at the Hanover Theatre, this culturally rich area offers a blend of history and modernity like no other. Indulge in the local delicacies like the famous Worcester-style pizza, while catching a game of the Worcester Red Sox at Polar Park. Surrounded by lush parks and recreational areas like Elm Park and Green Hill Park, Worcester provides the perfect backdrop for a fulfilling career. Dive into our job listings and unlock a world of possibilities in this captivating city!

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