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Senior Research Associate, CMC

South San Francisco, CA 94080

Posted: 11/17/2022 Employment Type: Direct Hire/Perm Job Category: Scientific Job Number: 512559 Is job remote?: No Country: United States

Job Description


Description:
Salary Range: 90-110K/yr

• The Senior Research Associate will be a process chemist contributing to the CMC team by 
conducting laboratory-based chemistry research and development activities to support pipeline of pre-clinical and clinical programs. 
• The candidate is expected to exercise a broad working knowledge of synthetic organic chemistry  reactions and techniques to perform process optimization, scale-up, and other experimental  development studies. 
• With guidance from their supervisor and project leadership, the Research Associate will  integrate data from our Medicinal Chemistry group and external vendors into the design of  experiments to support process development. 
• The position offers potential for scientific growth and gain of CMC and cGMP knowledge while  working on novel therapeutics to address unmet medical needs.

MAJOR DUTIES AND RESPONSIBILITIES:
• Execute bench-scale experiments (from vial to overhead stirrer/jacketed reactor setups) to find 
optimal synthetic routes for key intermediates/final compounds
• Requires a basic understanding of reactivity and functional group compatibility with the 
materials and reagents employed
• Requires hands-on knowledge of compound characterization/structural elucidation techniques 
including, but not limited to, NMR and mass spectrometry
• Develop crystallizations, analyzing isolated solids in multiple ways (solubility, DSC, visual 
microscopy)
• Maintain detailed, clear, and accurate records of experiments in electronic notebooks 
• Integrate key experiments/data into technical reports and tech transfer documentation
• Present concise summaries & interpretations of experimental results in group meetings
• Help maintain the efficiency of the CMC organization through activities such as inventory 
management, sample shipments, etc. as needed
EDUCATION REQUIREMENTS: 
• BS or MS in chemistry with synthetic chemistry experience
EXPERIENCE REQUIREMENTS: 
• 3-5 years of industry experience in a process chemistry setting
OTHER QUALIFICATIONS: 
• Experience working safely in a fast-paced lab environment
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