Senior Research Associate, Formulation
50 Northern Avenue, Boston, MA 02210 Boston, MA 02210 US
Pay range: $35-$40
Senior Research Associate – Formulation Development Formulation Development seeks a dedicated scientist to join a diligent team working to discover, develop, and commercialize therapies for patients with serious diseases. The incumbent will join our innovative preclinical formulation group to play a hands-on role in driving the selection of drug candidates for clinical evaluation. The ideal candidate has a fundamental understanding of chemistry and physics and has direct experience in a research laboratory (e.g., undergraduate research, cooperative training program or summer internship). The candidate must comfortably take initiative, be curious, and show resilience in solving complex problems.
Key Duties and Responsibilities: • Execute laboratory experiments and interpret analytical data to meet established project timelines • Prepare preclinical formulations of small molecule drug candidates to be dosed by various routes of administration for pharmacology, PK, and toxicology studies • Evaluate the physicochemical/solid state properties of lead candidates to aid in advancement to the clinic (e.g., solubility and stability in bio-relevant media, thermal analysis, etc) • Maintain accurate and complete laboratory notebook in real time • Comply with all relevant ethical, safety, and training procedures
Knowledge and Skills: • A degree in chemistry, pharmaceutical chemistry, biochemistry, chemical engineering (or closely related major) with coursework in at least the following branches: physical, analytical, organic, and biochemistry • Experience as an Undergraduate Researcher Coop, or Intern conducting experiments in the laboratory (beyond course-associated work) • Working knowledge of solid-state analytical techniques including: XRPD, DSC, TGA, DVS considered a plus • HPLC experience considered a plus • Strong technical writing and excellent verbal communication skills
Minimum Qualifications: Master’s degree in chemistry, pharmaceutical chemistry, biochemistry, chemical engineering (or closely related major) with 0+ years The candidate will have completed coursework in at least the following areas: physical, analytical, and organic chemistry
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