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Senior Research Associate - Molecular Biology

SOUTH SAN FRANCISCO, CA 94080

Posted: 04/19/2024 Employment Type: Contract Job Category: Scientific Job Number: 601292 Is job remote?: No Country: United States

Job Description

As a Senior Research Associate -  Molecular Biology , you will work with a team of scientists and research associates to advance our gene editing technologies, enabling the discovery of new therapeutics, and improving their function so they can be safely and effectively delivered to patients. You will primarily be performing tissue culture-based assays to evaluate gene modifications as measured by NGS and flow cytometry. Primary Responsibilities:
  • Support all tissue culture needed to measure gene editing therapeutics, using both primary and immortalized cell lines
  • Perform transfections, including with LNPs, transductions and electroporations of nucleic acids at 96-well scale
  • Perform tissue culture assays for measuring gene modification outcomes via NGS and flow cytometry
  • Utilize and improve methods for high-throughput tissue culture experiments, including VIAFLO pipettes and liquid-handling robots
  • Produce RNA, LNP and virus research articles
Qualifications:
  • A minimum of 3 years of experience maintaining and transforming multiple immortalized cell lines, and primary cell lines
  • Experience with multiple transfection and transduction approaches: ie lipid-based transformations, lonza nucleofectors, and AAV and other viral transductions
  • Capable of running and maintaining cytometer and/or high-content imaging instruments, along with preparing samples to run on these instruments
  • Experience working with, and developing SOPs for, tissue culture automation tools
  Education / Experience:  
  • Bachelor's degree in Molecular Biology or related field and 6+ years of experience in the biotech industry, or Master’s degree in Molecular Biology or related field and 4+ years in the biotech industry.
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