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Senior Research Associate

Seattle, WA 98109

Posted: 02/05/2024 Employment Type: Contract Job Category: Scientific Job Number: 594530 Is job remote?: No Country: United States

Job Description


Target Pay Rate: 40-58.78/hr **salary will be commensurate with experience 

Job Description:

The senior research associate/associate scientist will join the Gene Delivery Process and Analytical Development (GDPAD) organization supporting process development, production, and characterization of viral vectors, which are critical to generating groundbreaking cell therapies.

The associate will join the AAV Platform Development team working on vector biology and molecular optimization initiatives intended to drive next-generation viral vector platform development. Specifically, in the pursuit of end-to-end assessment of novel technologies and approaches, the associate will seek to become highly proficient in upstream production and downstream purification of recombinant AAV, while gaining familiarity with AAV analytical methods and their interpretation in the context of AAV attributes and biology. The associate will also have the unique opportunity to be exposed to a wide range of highly novel molecular designs, and to work collaboratively with a range of different groups doing different types of rAAV development.

Responsibilities:
  • Execute and troubleshoot upstream and downstream process development experiments supporting next-generation AAV production
  • Manage the flow of samples and data and perform analyses
  • Assist in the design of experiments and interpretation of data
  • Optimize workflows for assessing new constructs and modes of production
  • Provide experimental design and executional support to team members in adjacent and related functions (e.g. clinical development programs, high throughput process development, etc.)
  • Support research-to-development transition endeavors, including early-stage/pipeline molecular assessment activities
  • Actively participate and support lab maintenance and continuous improvement initiatives
  • Maintain accurate and detailed laboratory notebook and documentation
  • Summarize and present data in group meetings and contribute to group discussions and team strategy
  • Author technical reports and study memos
Top Skills:
• 2+ years of hands-on lab work on biotech industry
• Experience in process development: Upstream process development and/or mammalian cell culture OR Downstream process development/purification
• Bachelor's degree in STEM field
Basic Qualifications:
  • STEM degree with 2+ years of relevant industry experience; title/compensation will ultimately be commensurate with education, experience, and skillset
  • Experience with suspension culture of mammalian cells in shake flasks and small stirred tank bioreactors
  • Hands on experience in process development
  • Independently motivated with ability to work in teams
  • Ability to communicate clearly and concisely through oral presentation and technical writing
  • Ability to leverage literature, internal and external resources to solve problems
  • Desire to identify and advance the cutting edge
  • Possess a growth mindset and the ability to thrive in a fast-paced, highly collaborative environment

Preferred Qualifications:
  • Degree in biological or chemical engineering, biochemistry, or bio-related field
  • Hands-on experience in downstream purification including chromatography and filtration
  • Experience in the development of viral vectors (e.g. adeno-, retro-, lenti-), including successful transfer for GMP manufacturing
  • Experience with transfection-based processes
  • Experience with upstream processes intensification e.g. fed batch and perfusion development, process-analytical technology (PAT)
  • Experience with single-use technologies
  • Experience with late-stage development

Additional Job Requirements:
Position Handles Hazardous Materials

The staffing industry has seen an increase in people falsely representing themselves as recruiters to gather personal information from job seekers. For your safety, do not provide sensitive data to anyone you have not spoken with thoroughly and never provide banking information during the application process. Candidate safety is a top priority at Planet Pharma.

Planet Pharma and The Planet Group of Companies are equal opportunity employers. It is our practice not to discriminate against any employee or applicant based on any criteria, condition or basis protected by laws or regulations in the locations where we do business. All qualified applicants are encouraged to apply. We celebrate diversity and are committed to providing an environment of mutual respect. We believe that diversity, equity and inclusion enable us to better meet our mission and values while serving our clients across the globe. If you have a disability or handicap and would like us to accommodate you in any reasonable way, please inform your recruiter, or contact us, so that we can discuss the appropriate alternatives available.

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Although this hasn't been an issue at Planet Pharma, the staffing industry has seen an increase in people falsely representing themselves as recruiters to gather personal information from job seekers. For your safety, do not provide sensitive data to anyone you have not spoken with thoroughly and never provide banking information during the application process. Candidate safety is a top priority at Planet Pharma.