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Senior Research Associate

Seattle, WA 98109

Posted: 05/31/2023 Employment Type: Contract Job Category: Scientific Job Number: 566626-1 Is job remote?: No Country: United States

Job Description

The Cell Therapy Product Sciences department is seeking two Senior Research Associate to support the development of gene engineered T cell products. Product Sciences is responsible for developing and executing mechanism of action and characterization studies to support the development of gene-engineered T cell therapies. The primary focus of the Senior Research Associate - Product Sciences role will be to build CAR/TCR T cell product and process understanding in support of early and late-stage CAR T with a particular focus on exploratory/investigational needs for late-stage programs. Successful candidates will have a very strong foundation in cell-based assays (flow cytometry, proliferation, cytotoxicity, cytokine release, etc) and some background in human T cell biology and/or other immune cell types. Experience with implementation and optimization of a broad range of in vitro cell-based and molecular assays is critical (especially multi-color flow cytometry and cell culture). This role is highly collaborative and requires attention to detail, a healthy sense of urgency, a strong desire to learn, and a passion for exploratory and investigational science. Furthermore, a demonstrated ability to support cross-functional teams and independently design and execute studies to meet project goals is very highly desirable (albeit not a requirement and will depend on the applicant’s individual qualifications).

Primarily, support late-stage drug product and manufacturing process understanding by performing exploratory studies and investigational analyses including experimental design and execution, statistical/correlative analyses of existing data sets, writing technical reports, presenting data, etc.

Additionally, depending on the applicant’s individual qualifications, duties and responsibilities include the following:
· Design and deploy in-depth characterization of gene engineered T cells using flow cytometry, genome-wide expression analysis, metabolic profiling, and/or additional cutting-edge analytical techniques.
· Participate in cross-functional teams to support the development of gene engineered T cell therapeutic platforms.
· Identification and development of novel analytical approaches for interrogating gene engineered T cell function.
· Develop and maintain relationships with external collaborators and service providers.
· Serve as T cell biology subject matter expert in multidisciplinary team setting, that includes non-clinical, clinical, regulatory, and CMC functions.
· Perform and manage instrument and method troubleshooting
· Author, review, and approve technical documents, including methods, protocols, reports, and SOPs
· Learn and apply ICH/FDA/EMEA guidance and current thinking.

Senior Research Associate Level:
BS and 5+ years; or MS and 2+ years in Biology, Cell Biology, Immunology, Bioengineering, or relevant discipline;

The staffing industry has seen an increase in people falsely representing themselves as recruiters to gather personal information from job seekers. For your safety, do not provide sensitive data to anyone you have not spoken with thoroughly and never provide banking information during the application process. Candidate safety is a top priority at Planet Pharma.

Planet Pharma and The Planet Group of Companies are equal opportunity employers. It is our practice not to discriminate against any employee or applicant based on any criteria, condition or basis protected by laws or regulations in the locations where we do business. All qualified applicants are encouraged to apply. We celebrate diversity and are committed to providing an environment of mutual respect. We believe that diversity, equity and inclusion enable us to better meet our mission and values while serving our clients across the globe. If you have a disability or handicap and would like us to accommodate you in any reasonable way, please inform your recruiter, or contact us, so that we can discuss the appropriate alternatives available.

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Although this hasn't been an issue at Planet Pharma, the staffing industry has seen an increase in people falsely representing themselves as recruiters to gather personal information from job seekers. For your safety, do not provide sensitive data to anyone you have not spoken with thoroughly and never provide banking information during the application process. Candidate safety is a top priority at Planet Pharma.