Senior Research Associate in Vitro, Biology
181 Oyster Point Blvd South San Francisco, CA 94080 US
Pay Rate Range: $80-90/hr
The Biology Department is looking for a qualified Senior Research Associate with expertise in protein expression, purification, and assay development to understand mechanisms of disease and treatment. The successful candidate will join a multi-disciplinary team and support our structural biology platform in drug discovery effort by protein cloning, expression and purification, and biochemical and cell-based assay development to translate SAR insight into testable hypotheses. This senior research associate will play a major role in performing, improving, and automating protein expression workflows, from cloning to purification. The ideal candidate will be highly motivated, detail-oriented, and can collaborate in a cross-functional team. Responsibilities:
This Senior Research Associate will play a major role in performing, improving, and automating protein expression workflows, from cloning, purification, to characterization. Design and execute protein expression and purification experiments in a variety of expression systems, from bacteria to mammalian cells Validate expressed proteins using SDS-PAGE, and western blot Performing in vitro and cell-based potency and ELISA assays Independently conduct experiments; maintain detailed records of experiments and outcomes; and work in collaboration with team members within and across departments
Contribute to understanding protein structure and function that drives drug discovery efforts. Present findings to the immediate team and broader company Opportunities for new technology development with a strong team of scientists
Skills: Qualifications: 2+ years of experience directly working with relevant molecular biology and protein methods, including cloning methods, primer/vector design, plasmid isolation and sequencing, protein expression and purification in a variety of expression systems, from bacteria to mammalian cells Experience using an ELN Interest in laboratory automation, data analysis, and data visualization Experience with biochemical analytical methods and assay development Good understanding of protein biochemistry, enzymology, and protein purification processes Ability to work effectively and collaboratively on cross-functional projects teams Excellent oral, presentation, and written communication skills Education: Masters degree in life sciences, Biochemistry, Biophysics or a related area
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