Skip to content

Job Openings

Senior Scientist, Analytical Chemistry

South San Francisco, CA 94080

Posted: 01/09/2025 Employment Type: Direct Hire/Perm Job Category: Scientific Job Number: 616515 Is job remote?: No Country: United States

Job Description

Senior Scientist, Analytical Chemistry
The Position: 

We are seeking an experienced, energetic, and enthusiastic individual to join the Analytical and Formulation Sciences group within the Drug Discovery department. This lab-based role is perfect for someone eager to deepen their expertise in analytical, formulation, and separation sciences along with physical chemical property measurement.  

In this role, you will play a crucial part in supporting the Drug Discovery group as we strive to bring new medicines to patients. As a key member of project teams, you’ll collaborate with experts in medicinal chemistry, DMPK, pharmacology, and biomarker departments. Together, you’ll help advance our programs from initial screening to clinical nomination. You’ll have the opportunity to work with top-of-the-line analytical instrumentation, including LCMSMS, Agilent HPLC 1260, Waters LCMS, PLM, Dissolution Apparatus, and a Rigaku Miniflex XRPD.  

Your Impact: 
  • Independently develop chromatography methods with different modes such as normal phase, reverse phase, chiral and achiral for diverse compounds to support Drug Discovery projects.
  • Apply extensive hands-on experience to operate, maintain and troubleshoot mass spectrometers such as single-Q, Triple-Q, Q-TOF, Orbitrap, as well as SFC chromatography instruments.
  • Independently develop LCMS methods for characterizing advanced lead compounds, including but not limited to impurity profile, degradant identification, and structure elucidation of major impurities and degradants.
  • Conduct solid form measurements including thermodynamic solubility, particle size, polyforms, melting point, salt, and water content analysis.
  • Perform solid form measurements for advanced lead compounds; including solubility, particle size and polyform assessment, melting point, salt and water content of each lot.
  • Author analytical protocols and reports. Provide suggestions and troubleshoot potential issues in ongoing drug discovery projects. Coordinate and provide oversight during assay transfer between the company and external partner groups.
  • You will provide scientific mentorship and technical guidance for junior colleagues. 

Skills and Qualifications: 
  • PhD with 7+ years or Master's with 10+ years of relevant experience in an academic, biotech, or pharmaceutical industry
  • Degree in Analytical Chemistry, Organic Chemistry, Biochemistry, Pharmaceutical Sciences, or related discipline
  • Extensive hands-on experience with HPLC, LCMS, LCMSMS, ELSD, or CAD, Karl Fisher, Ion Chromatography, DSC, and reverse phase/normal phase/chiral chromatography
  • Strong method development skills including experience with reverse phase, normal phase and SFC liquid chromatography, mass spectrometry, fragmentation mass spectrometry, ELSD/CAD, and SFC separations.
  • Experience in analytical assay development, quantitative analysis, impurity elucidation, high throughput QC, and library screening.
  • Excellent interpersonal and leadership skills for cross-functional collaboration.

The staffing industry has seen an increase in people falsely representing themselves as recruiters to gather personal information from job seekers. For your safety, do not provide sensitive data to anyone you have not spoken with thoroughly and never provide banking information during the application process. Candidate safety is a top priority at Planet Pharma.

Planet Pharma is an equal opportunity employer. It is our practice not to discriminate against any employee or applicant based on any criteria, condition or basis protected by laws or regulations in the locations where we do business. All qualified applicants are encouraged to apply. We celebrate diversity and are committed to providing an environment of mutual respect. We believe that diversity, equity and inclusion enable us to better meet our mission and values while serving our clients across the globe. If you have a disability or handicap and would like us to accommodate you in any reasonable way, please inform your recruiter, or contact us, so that we can discuss the appropriate alternatives available.

Apply Online

Send an email reminder to:

Share This Job:

Related Jobs:

Login to save this search and get notified of similar positions.

About South San Francisco, CA

Ready to take the next step in your career journey? Explore our job opportunities in the vibrant area surrounding South San Francisco, California! Known for its proximity to the iconic Golden Gate Bridge and the bustling tech hub of Silicon Valley, this region offers unrivaled growth potential and a dynamic work environment. With a unique blend of culture, including the renowned SFMOMA art museum, the lively Castro District, and delectable cuisine like the famous sourdough bread at Boudin Bakery, South San Francisco is the perfect place to thrive professionally while enjoying the beauty of nearby parks like Golden Gate Park and the breathtaking views of the Pacific Ocean. Join us in discovering the endless possibilities for your career in this enchanting region!

Although this hasn't been an issue at Planet Pharma, the staffing industry has seen an increase in people falsely representing themselves as recruiters to gather personal information from job seekers. For your safety, do not provide sensitive data to anyone you have not spoken with thoroughly and never provide banking information during the application process. Candidate safety is a top priority at Planet Pharma.