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Sr. Research Associate - Cancer Immunology

Redwood City, CA 94063

Posted: 03/12/2024 Employment Type: Contract Job Category: Scientific Job Number: 599471 Is job remote?: No Country: United States

Job Description

Sr. Research Associate  - Cancer Immunology 

Our Client is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers.  The company’s R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding scientists in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

As a key member of our dynamic Biology team, you will have proven expertise in:

  • Mammalian cell culture.

  • Flow cytometry, including cell staining, processing, and data analysis.

  • Cell-based assay development using reagent kits, including but not limited to SDS PAGE/Western blot, ELISA, ELISpot, MSD, DNA/RNA extraction, PCR, RTqPCR.

  • Plate-based assays – including automation (comfortable using robotics for compound dilutions, additions), plate washers, plate readers, multichannel pipettes.

  • Excellent team member, collaborator, and communicator, eager to learn new techniques

  • Additional experience in the following a plus:

  • Immuno-oncology assays such as T cell proliferation, suppression and killing assays, antigen presentation assays, phagocytosis assays, etc.

    • Experience with primary immune cells, including human PBMC handling, isolation and differentiation.

    • Incucyte cell-based assays.

    • Ex vivo experiments, including murine tissue collection, dissociation, and processing for downstream applications.

Required Experience, Skills, and Education:

  • Bachelor’s degree or Master’s degree in Science with 3+ years of experience in a cell biology/cellular assay development role. Title will be adjusted according to experience.

  • Deep expertise with mammalian cell culture across a variety of cell types (primary and immortalized) and growth conditions. Demonstrated experience handling (maintaining, passaging, plating) multiple cell lines at once.

  • Hands-on experience with a wide range of cellular assay techniques (including, but not limited to, Flow Cytometry, Western Blot, MSD, qPCR) suitable for target identification and/or compound characterization.

  • Immuno-oncology related experience is a plus.

  • Rigorous, quantitative, attention to detail, keen to maximize efficiency.

  • Highly organized, and excellent record keeping skills.

  • Excellent written and verbal communication skills to facilitate collaboration with project and departmental teams.

  • Innovative, proactive team-player with high energy who will thrive in our fast-paced drug discovery and development environment.

Requires that all personnel and visitors to its offices be fully vaccinated against COVID-19. 
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About Redwood City, CA

Ready to embark on an exciting career opportunity in the vibrant area around Redwood City, California? Nestled in the heart of Silicon Valley, this thriving region offers a perfect blend of innovation, growth, and charm. From the bustling tech scene to the serene beauty of Redwood City's parks, like Edgewood Park and Pulgas Ridge Preserve, there's something here for everyone. Immerse yourself in the local culture by visiting the Fox Theatre or exploring art galleries like The Art Center and Redwood City Art Kiosk. With a bustling food scene offering everything from trendy cafes to authentic Mexican cuisine, it's no wonder that Redwood City is a top choice for job seekers looking to thrive in a dynamic environment. Browse our job listings today and take the next step towards a fulfilling career in this captivating locale!

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