Sr. Scientist
280 UTAH AVE., SUITE 200 SOUTH SAN FRANCISCO, CA 94080 US
Job Description
following areas:
- Building improved CRISPR-Cas-related and novel systems that enable therapeutic
genome and transcriptome engineering
- Demonstrating the functional impact of our therapeutic candidates with in vitro and in
vivo model systems
- Enhancing and deepening our genomics analysis of candidate therapies in our pipeline
- Developing in vivo delivery approaches for our candidate therapies using AAV and LNP platforms
- Leveraging the literature to identify and implement new ideas and approaches
- Mentoring and managing junior scientists/associates by leading discussions of new ideas and/or approaches, challenging ideas and interpretations, and cultivating teams to help solve challenging experimental questions
- And finally, combining all of these to develop novel therapeutic products that change
the lives of patients
What we’re looking for:
- A PhD in a biological discipline, or a masters with a minimum of four years of experience in independent experimental design, focused on bioengineering to change the behavior of cells through control of the genome or transcriptome
- A creative thinker with a track record of high-quality data generation
- An experimentalist ready and able to drive to the full cycle of design/build/test/analyze
What characterizes a top candidate (preferred but not required):
- Demonstrated track record of characterizing, developing or optimizing genome or
transcriptome modification systems
- Experience engineering protein-DNA and/or protein-RNA interactions
- Experience using gene-editing tools for human therapeutics
- Experience establishing pooled or other high throughput screens
Salary range: 150k-160k range based on experience.
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