Temp Senior Research Associate, Cancer Cell & Systems Biology
700 Saginaw Drive Redwood City, CA 94063 US
Job Description
The Opportunity:Â
As a key member of the Biology team, you will:Â
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Independently conduct key experiments to support new target identification and validation efforts
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Contribute to the development of and perform in vitro and cell-based assays to support identification of tractable chemical matter targeting new oncogenic targets in RAS-driven cancers
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Apply various cellular, molecular, and genetic techniques to characterize and enhance our mechanistic understanding of novel anti-cancer agents
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Maintain cultures of multiple human cancer cell lines simultaneously to support experimental effortsÂ
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Perform various cell-based assays to interrogate effects of inhibitors on signaling pathways
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Perform microplate-based quantitative assays using reagent kits
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Analyze and interpret experimental data, formulate testable hypotheses and propose follow up experiments within project scope, and present results at internal meetings
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Collaborate with team members to generate novel insights into key drivers of RAS-driven cancers
Required Experience, Skills, and Education:Â
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Bachelor’s degree or Master’s degree in Cell/Molecular Biology, Biochemistry, Biology, Genetics, or related fieldÂ
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6+ years of experience in an industry position or academic lab involving cell/tissue culture and cell/molecular biology OR 3-5 years of experience with a Master’s degree
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Demonstrated proficiency with a wide range of cell and molecular biology techniques (e.g., cell line engineering, SDS-PAGE/Western blot, molecular cloning, DNA/RNA preparation, PCR, qPCR, etc.)
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Proficiency with cell/tissue culture, including the ability to maintain multiple human cancer cell lines simultaneously with strong aseptic technique
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Rigorous, detail-oriented, and quantitative experimentalist
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Proven ability to proactively and independently problem solve with minimum guidance
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Highly organized, with excellent record keeping and written/verbal communication skills
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Demonstrated ability to multi-task, prioritize, and complete tasks efficiently to meet project deadlines
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Innovative and adaptable team-player with an eagerness to learn new techniques
Note:Â This is a lab-based role. Therefore, it is expected that the team member be on-site 5 days per week.
Preferred Skills:
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Demonstrated proficiency with relevant assay readout technologies (e.g., CellTiter-Glo, AlphaLISA, MSD)
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Experience with automation (e.g., robotic liquid handlers, cell seeders, etc.)
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Familiarity with data processing, curve fitting, and visualization tools to analyze small and large datasets (e.g., GraphPad Prism, Genedata Screener, D360, or Spotfire)
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