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Translational Research Scientist - II (Associate)

South San Francisco, CA 94080

Posted: 02/06/2024 Employment Type: Contract Job Category: Scientific Job Number: 598313 Is job remote?: No Country: United States

Job Description


Target Pay Rate: 50-67.86/hr **salary will be commensurate with experience 

Job Description:


The Cytometric profiling group within the Profiling and Expression department is seeking a motivated and creative scientist capable of working in a collaborative environment to advance preclinical immunology and oncology drug development programs.

The qualified candidate will be involved in data generation and analysis to support the following types of studies:
  • Immunophenotyping human and non-human primate blood and tissue samples using high dimensional spectral flow cytometry
  • Identifying and validating target engagement and pharmacodynamic biomarkers for drug candidates
  • Utilizing single cell technologies to enable target identification and biomarker discovery
  • Functional assay development using therapeutic antibodies
  • Novel technology assessments and platform development efforts
  • Support day to day functioning of Flow Cytometry Core Lab

The candidate will also be expected to attend team meetings, deliver clear and well-articulated presentations and be an active participant in scientific discussions.

Qualifications:
Educational Requirements B.S or M.S in Immunology, Biology, or a related discipline with 5-8 years of relevant industry experience. Candidates with more advanced degrees (PhD) are highly encouraged to apply. Required Experience and Skills • A good understanding of immunological concepts • Expertise in aseptic cell culture techniques • Experience with blood and/or tissue processing for primary cell isolation • Experience with multi-color flow cytometry (preferably with BD Biosciences or Beckman Coulter flow cytometers) and proficiency in FlowJo analysis • Experience with functional assay development and secreted cytokine analysis (ELISA, MSD, Luminex) • Excellent interpersonal and communication skills • Attention to detail and ability to maintain meticulous records • This position is lab-based, and the candidate will be expected to be on site on all working days Additional Experience and Skills • Experience with any single cell genomics (10X Genomics, BD Rhapsody, or HIVE-seq) and/or proteomics (IsoPlexis) platforms • Experience with high dimensional spectral flow cytometry, preferably with Cytek Aurora spectral cytometer • Proficiency with TIBCO Spotfire, GraphPad Prism and/or IsoSpeak software
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