Job Details
Posted 23 October, 2026
Job Id: 631939
Associate Scientist, HTS & NGS
Job Description
Location: Cambridge, MA – Onsite
Position Summary: biotech client is seeking a highly motivated contract Associate Scientist to join our HTS-NGS operations team and work with an enthusiastic team of highly skilled scientists. The ideal candidate for this lab-based position is committed to delivering high quality results in a timely manner. This is an exciting opportunity to be part of a collaborative team and contribute to the development of next-generation RNA editing technology and therapeutics in a fast-paced biotech company.?
Key Responsibilities:
- Independently design and execute high-throughput cell-based assays to support oligonucleotide platform and portfolio projects
- Perform amplicon-seq library preparation and quality control, operate and maintain NGS platforms and associated laboratory equipment
- ?Troubleshoot HTS assays, library preparation, and sequencing workflows as needed
- Analyze and present HTS-NGS data based on results in a team setting; collaborate with cross-functional teams to support lead discovery
- Support NGS scientists in operational tasks, including inventory management, assay development, and operations improvement
- Accurately document project and sample information, protocols, and experimental details through an Electronic Lab Notebook (ELN)
Required Qualifications:
- MS with 3+ years or BS with 5+ years of experience in molecular biology, cell biology, or related field
- 1+ years of hands-on experience with high-throughput assays and automated workflows
- Experience with cell culture techniques, including plating and transfection in 96/384-well formats
- Experience with NGS assays: amplicon-seq and RNA-seq, including primer design, library preparation, quantification, and data quality control
- Demonstrated expertise in molecular biology techniques: RNA/DNA isolation, transfection, PCR/qPCR, gel electrophoresis
- Familiarity with liquid handling systems (e.g., Viaflo96/384, HiRes/Certus Flex, Tempest) is highly preferred
- Hands-on experience with next-generation sequencing platforms and equipment including Illumina (MiSeq i100), Qubit, Tape Station, and Fragment Analyzer is highly preferred
- ?Experience with LIMS systems (Benchling) and project management tools (Jira/Confluence)??
- ?Strong troubleshooting skills and ability to suggest and implement new solutions independently
- Excellent written and verbal communication skills with attention to detail
- Ability to thrive in a fast-paced and evolving environment
Equal Opportunity Employer
We are proud to be an equal opportunity employer. We welcome and encourage applications from all qualified candidates regardless of race, sex, gender identity or expression, disability, age, religion or belief, sexual orientation, or any other characteristic protected by applicable laws and regulations. It is our policy not to discriminate against any applicant or employee, and we are committed to fostering a diverse, inclusive, and respectful work environment across all locations in which we operate. We believe that diversity, equity, and inclusion are fundamental to our mission and enhance our ability to serve clients globally. If you have a disability or require any reasonable accommodations during the application or interview process, please inform your recruiter or contact us directly so that we can explore the appropriate arrangements.
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