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Translational Research Scientist - II (Associate)
213 East Grand Avenue S San Francisco, CA 94080 US
Job Description
Target Pay Rate: 75-88.09/hr **salary will be commensurate with experience
Job Description:
The Anatomic Pathology group within the Profiling & Expression department is seeking a motivated, experienced scientist with experience in multiplexed immunofluorescence assay development and digital image analysis to support discovery and translational research in our pathology group in South San Francisco.
The Successful Candidate will:
• Perform validation and quality check of the analysis readout on multiplexed immunofluorescence images
• Perform image preprocessing tasks according to established SOPs, including metadata extraction, output quality control, and secure data transfer to cloud storage.
• Assist in evaluating and implementing new algorithms to enhance the image analysis pipeline, such as cell segmentation improvements, tissue classification, and cell phenotyping.
• Assist with the transfer of data and image-related information for analysis, facilitating smooth collaboration between teams.
• Coordinating with IT to
o Gather and document feedback from users on image analysis workflows and tools.
o Address user pain points, define requirements, and improve tool functionality.
o Lead user experience testing, working with IT to implement improvements and optimize tools for production use
o Maintain and update image analysis computers to ensure they remain optimized for routine tasks
• Define and document requirements for new tools and ensure their successful deployment.
• Provide administrative support for multiplex IHC related work, including reagent ordering, capital equipment purchasing, document and maintain SOPs for image processing and analysis workflows.
• Interact smoothly with scientists, computer scientists, and informatics/IT staff, both internally and externally
Qualifications:
Required Experience and Skills: • B.S with minimum 5+ years’; Masters with 3+ years'; PHD with 1-2 years' of relevant work experience in industry or academia • Experience with immunohistochemistry and multiplexed immunofluorescence assay development • Experience using digital image analysis software and spatial imaging platforms such as HALO, Visiopharm, QuPath, digital slide scanning, multiplex spectral imaging, Akoya Polaris, Phenocycler/Fusion. • Strong organizational abilities and communication skills Preferred Experience and Skills: • High level of comfort with histology/microanatomy strongly preferred • Background in oncology and/or immunology • Programming skills with application in imaging (e.g. Python, MATLAB) data • Experience with version control environments, such as Git • Experience with high-performance Linux cluster and cloud computing • Familiarity with client--servers and cloud computing infrastructure
Equal Opportunity Employer: We are proud to be an equal opportunity employer. We welcome and encourage applications from all qualified candidates regardless of race, sex, gender identity or expression, disability, age, religion or belief, sexual orientation, or any other characteristic protected by applicable laws and regulations. It is our policy not to discriminate against any applicant or employee, and we are committed to fostering a diverse, inclusive, and respectful work environment across all locations in which we operate. We believe that diversity, equity, and inclusion are fundamental to our mission and enhance our ability to serve clients globally. If you have a disability or require any reasonable accommodations during the application or interview process, please inform your recruiter or contact us directly so that we can explore the appropriate arrangements.
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