Job Details
Posted 6 July, 2026
Job Id: 627511
*Confidential Search* Principal Scientist, ADC Cellular Trafficking and Transporter Biology
Job Description
Seeking an accomplished and highly driven Principal Scientist to lead from the bench in-depth characterization of lysosomal trafficking and internalization dynamics of next-generation antibody-drug-conjugates (ADCs). This role is a critical lab-facing leadership position with ownership over lab management, confocal imaging assay development, data integrity, and mechanism-of action studies across discovery and early development programs.
Key Responsibilities
Scientific Leadership
- Develop and execute cellular assays for interrogation of next-generation ADC lysosomal trafficking dynamics across multiple ADC therapeutic programs, ensuring alignment with program and company objectives
- Serve as the confocal microscopy and high-content imaging technical expert, mentoring a team of scientists and guiding experimental design and interpretation
- Partner closely with cross-functional leaders as the subject-matter expert for lysosomal transporter biology and to integrate in vitro data with in vivo, translational, and discovery efforts
- Lab management responsible for equipment and reagent ordering
Qualifications
Education & Experience
- PhD in Pharmacology, Biology, Cancer Biology, Molecular Biology, or a related discipline with 4+ years of relevant industry experience; MS with 8+ years of relevant industry experience. Demonstrated experience leading in-depth cellular trafficking mechanism-of-action studies for biologics or antibody-based therapeutics
Equal Opportunity Employer
We are proud to be an equal opportunity employer. We welcome and encourage applications from all qualified candidates regardless of race, sex, gender identity or expression, disability, age, religion or belief, sexual orientation, or any other characteristic protected by applicable laws and regulations. It is our policy not to discriminate against any applicant or employee, and we are committed to fostering a diverse, inclusive, and respectful work environment across all locations in which we operate. We believe that diversity, equity, and inclusion are fundamental to our mission and enhance our ability to serve clients globally. If you have a disability or require any reasonable accommodations during the application or interview process, please inform your recruiter or contact us directly so that we can explore the appropriate arrangements.
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